Research output per year
Research output per year
Personal profile
Research interests
I am a developmental biologist interested in the complex processes that control the intricate development of the craniofacial skeleton. My work has focused on neural crest cells, a magnificent, multipotent cell population that gives rise to the majority of the craniofacial skeleton during embryogenesis. I have used mouse and zebrafish models to study the pathophysiology of human craniofacial disorders and I have recently discovered a novel role for the transcription factor Ronin in craniofacial development and ribosome biogenesis. I am currently interested in using molecular biology, histology, and genetic approaches to better understand the transcriptional regulation of neural crest cells and their subsequent differentiation into facial bone and cartilage.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Research Associate, Baylor College of Medicine
2015 → 2021
Postdoctoral Fellow, Lab of Dr Paul Trainor, Stowers Institute for Biomedical Research
2010 → 2015
PhD, Developmental Genetics, New York University School of Medicine
2005 → 2010
Master, Cell Biology, New York University School of Medicine
2005 → 2007
Bachelor, Biology ; Molecular Biology and Biochemistry, University of Massachusetts. Amherst
2001 → 2005
External positions
Research Associate, Lab of Dr. Ross Poché , Baylor College of Medicine
2015 → 2021
Post-Doctoral Researcher, Lab of Dr. Paul Trainor , Stowers Institute for Medical Research
2010 → 2015
Graduate Student Researcher, Lab of Dr. Jeremy Nance, Sackler Institute of Graduate Biomedical Sciences, New York University School of Medicine
2005 → 2010
Undergraduate Researcher, Lab of Dr. Rolf Karlstrom, University of Massachusetts. Amherst
2003 → 2005
Keywords
- Q Science (General)
- Developmental Biology
- Embryology
- Neural crest
- Craniofacial Development
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Collaborations and top research areas from the last five years
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Dynamic regulation and requirement for ribosomal RNA transcription during mammalian development
Falcon, K. T., Watt, K. E. N., Dash, S., Zhao, R., Sakai, D., Moore, E. L., Fitriasari, S., Childers, M., Sardiu, M. E., Swanson, S., Tsuchiya, D., Unruh, J., Bugarinovic, G., Li, L., Shiang, R., Achilleos, A., Dixon, J., Dixon, M. J. & Trainor, P. A., 2 Aug 2022, In: Proceedings of the National Academy of Sciences of the United States of America. 119, 31, e2116974119.Research output: Contribution to journal › Article › peer-review
Open Access -
Mutations in Hcfc1 and Ronin result in an inborn error of cobalamin metabolism and ribosomopathy
Chern, T., Achilleos, A., Tong, X., Hill, M. C., Saltzman, A. B., Reineke, L. C., Chaudhury, A., Dasgupta, S. K., Redhead, Y., Watkins, D., Neilson, J. R., Thiagarajan, P., Green, J. B. A., Malovannaya, A., Martin, J. F., Rosenblatt, D. S. & Poché, R. A., Dec 2022, In: Nature Communications. 13, 1, 134.Research output: Contribution to journal › Article › peer-review
Open Access -
Nr6a1 controls Hox expression dynamics and is a master regulator of vertebrate trunk development
Chang, Y. C., Manent, J., Schroeder, J., Wong, S. F. L., Hauswirth, G. M., Shylo, N. A., Moore, E. L., Achilleos, A., Garside, V., Polo, J. M., Trainor, P. & McGlinn, E., Dec 2022, In: Nature Communications. 13, 1, 7766.Research output: Contribution to journal › Article › peer-review
Open Access -
Mouse models to study the pathophysiology of combined methylmalonic acidemia and homocystinuria, cblC type
Chern, T., Achilleos, A., Tong, X., Hsu, C. W., Wong, L. & Poché, R. A., 1 Dec 2020, In: Developmental Biology. 468, 1-2, p. 1-13 13 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Foxc2 is required for proper cardiac neural crest cell migration, outflow tract septation, and ventricle expansion
Inman, K. E., Caiaffa, C. D., Melton, K. R., Sandell, L. L., Achilleos, A., Kume, T. & Trainor, P. A., Dec 2018, In: Developmental Dynamics. 247, 12, p. 1286-1296 11 p.Research output: Contribution to journal › Article › peer-review
Open Access