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Personal profile

Research interests

-Asymmetric Organic Synthesis

-Design, synthesis and biological evaluation of bioactive compounds

-Fragment-based drug discovery

-Antibiotics, tumberculosis-drugs, anticancer compounds, natural products, UV-filter/antioxidant protective compounds

Education/Academic qualification

PhD, Imperial College London

1 Oct 200430 Sep 2007

Bachelor, Aristotle University of Thessaloniki

1 Oct 200021 Jul 2004

External positions

Special Teaching Scientist, Cyprus University of Technology

1 Sep 20131 Jan 2014

Visiting Faculty Member, Frederick University, Cyprus

1 Sep 201331 Jan 2015

Research Associate, University of Cambridge

1 Mar 20107 Nov 2011

Senior Researcher, Demokritos National Centre for Scientific Research

1 Apr 200828 Feb 2010

Post-Doctoral Research Associate, Imperial College London

1 Oct 200731 Mar 2008

Fingerprint Dive into the research topics where Constantina Pyrkotis is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

Aminoglycosides Chemical Compounds
RNA Chemical Compounds
Decoding Chemical Compounds
Anti-Bacterial Agents Chemical Compounds
Binders Chemical Compounds
Triazoles Chemical Compounds
Alkenes Chemical Compounds
Biological Products Chemical Compounds

Research Output 2006 2014

2 Citations (Scopus)

Synthesis of triazole-functionalized 2-DOS analogues and their evaluation as A-site binders

Anastasopoulou, P., Kythreoti, G., Cosmidis, T., Pyrkotis, C., Nahmias, V. R. & Vourloumis, D., 15 Feb 2014, In : Bioorganic and Medicinal Chemistry Letters. 24, 4, p. 1122-1126 5 p.

Research output: Contribution to journalArticle

Triazoles
Aminoglycosides
Binders
RNA
Anti-Bacterial Agents
14 Citations (Scopus)

Designed spiro-bicyclic analogues targeting the ribosomal decoding center

Cottin, T., Pyrkotis, C., Stathakis, C. I., Mavridis, I., Katsoulis, I. A., Anastasopoulou, P., Kythreoti, G., Zografos, A. L., Nahmias, V. R., Papakyriakou, A. & Vourloumis, D., Jan 2011, In : ChemBioChem. 12, 1, p. 71-87 17 p.

Research output: Contribution to journalArticle

Decoding
Aminoglycosides
RNA
Ribosomes
Scaffolds

Synthesis of spiro-aminocyclitol analogs and their interaction with the ribosomal RNA

Pyrkotis, C., Katsoulis, I. A., Vourloumis, D., Papakyriakou, A., Cottin, T., Stathakis, C. I., Kythreoti, G., Anastasopoulou, P. & Mavridis, I., 2010.

Research output: Contribution to conferencePoster

Targeting bacterial RNA: Design and Synthesis of novel rigid structures with antibiotic activity

Pyrkotis, C., Stathakis, C. I., Katsoulis, I. A., Cottin, T., Papakyriakou, A., Zografos, A. L., Mavridis, I., Anastasopoulou, P., Kythreoti, G. & Vourloumis, D., 2010.

Research output: Contribution to conferenceAbstract

Chemical biology of novel rigid scaffolds with antibiotic potential

Pyrkotis, C., Vourloumis, D., Anastasopoulou, P., Mavridis, I., Katsoulis, I. A., Kythreoti, G., Papakyriakou, A., Zografos, A. L. & Nahmias, V. R., 2009.

Research output: Contribution to conferencePoster