Projects per year
Personal profile
Research interests
-Oxidation and anticancer activity of phenol complexes with transition metals and chelation activity of prenylated chalcones.
-Biomimetic radical chemistry – Biomolecular electron transfer.
-Complexation of flavonoids analogues with Vanadium and Cobalt and Zinc for use as anticancer drugs.
-Computer-aided synthesis of natural products and biological active ligands as anticancer agents.
-Synthesis and anticancer properties of Vanadium-tocopherol / xanthohumol conjugated molecules.
-Synthesis of fluorinated derivatives as probes for drug monitoring with 19FNMR.
-Characterization of biomimetic models of transition metals and investigation of their electron transfer activity.
-Molecular and biomolecular Spectroscopy and Computational Chemistry of mixed inorganic-organic metal complexes with medicinal applications.
-Identification and qualitative determination of biopolymers and macromolecules in food matrixes and in biomimetic models using advanced NMR techniques.
-Computer-aided drug design and discovery.
-Zinc binding and distribution with transport proteins and interactions of zinc-drug complexes with DNA.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
PhD, Chemistry, University of Cyprus
External positions
Editor, BMC Chemistry
Reviewer, Journal of Molecular Structure
Research and Development Scientist, M.N.K.E. CHEMICAL SERVICES
Reviewer , Molecular Simulation
Reviewer RSC Advances , Royal Society of Chemistry
Member, Royal Society of Chemistry
Reviewer Journal of Molecular Modeling, Springer Nature
Reviewer Board, Symmetry MDPI
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Projects
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In Silico Techniques Used for the Evaluation of Anticancer Metal-Based Compounds
Vlasiou, M., Mar 2023, In: Anti-Cancer Agents in Medicinal Chemistry. 23, 5, p. 490-491 2 p.Research output: Contribution to journal › Editorial › peer-review
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Binuclear VIV/V, MoVI and ZnII - hydroquinonate complexes: Synthesis, stability, oxidative activity and anticancer properties
Loizou, M., Papaphilippou, P., Vlasiou, M., Spilia, M., Peschos, D., Simos, Y. V., Keramidas, A. D. & Drouza, C., Oct 2022, In: Journal of Inorganic Biochemistry. 235, 111911.Research output: Contribution to journal › Article › peer-review
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Dft studies and molecular dynamics of the molecular and electronic structure of cu (Ii) and zn (ii) complexes with the symmetric ligand (z)-2-((3,5-dimethyl-2h-pyrrol-2-yl) methylene)-3,5-dimethyl-2h-pyrrole
Vlasiou, M. & Pafiti, K. S., 15 Oct 2022, In: Biointerface Research in Applied Chemistry. 12, 5, p. 5953-5968 16 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Ligand and Structure-Based Virtual Screening in Combination, to Evaluate Small Organic Molecules as Inhibitors for the XIAP Anti-Apoptotic Protein: The Xanthohumol Hypothesis
Mavra, A., Petrou, C. C. & Vlasiou, M. C., Aug 2022, In: Molecules. 27, 15, 4825.Research output: Contribution to journal › Article › peer-review
Open Access -
Metal-based complexes against SARS-CoV-2
Ioannou, K. & Vlasiou, M. C., 2022, (Accepted/In press) In: BioMetals.Research output: Contribution to journal › Review article › peer-review
Open Access