Projects per year
Personal profile
Research interests
-Oxidation and anticancer activity of phenol complexes with transition metals and chelation activity of prenylated chalcones.
-Biomimetic radical chemistry – Biomolecular electron transfer.
-Complexation of flavonoids analogues with Vanadium and Cobalt and Zinc for use as anticancer drugs.
-Computer-aided synthesis of natural products and biological active ligands as anticancer agents.
-Synthesis and anticancer properties of Vanadium-tocopherol / xanthohumol conjugated molecules.
-Synthesis of fluorinated derivatives as probes for drug monitoring with 19FNMR.
-Characterization of biomimetic models of transition metals and investigation of their electron transfer activity.
-Molecular and biomolecular Spectroscopy and Computational Chemistry of mixed inorganic-organic metal complexes with medicinal applications.
-Identification and qualitative determination of biopolymers and macromolecules in food matrixes and in biomimetic models using advanced NMR techniques.
-Computer-aided drug design and discovery.
-Zinc binding and distribution with transport proteins and interactions of zinc-drug complexes with DNA.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
PhD, Chemistry, University of Cyprus
External positions
Editor, BMC Chemistry
Reviewer, Journal of Molecular Structure
Research and Development Scientist, M.N.K.E. CHEMICAL SERVICES
Reviewer , Molecular Simulation
Reviewer RSC Advances , Royal Society of Chemistry
Member, Royal Society of Chemistry
Reviewer Journal of Molecular Modeling, Springer Nature
Reviewer Board, Symmetry MDPI
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Collaborations and top research areas from the last five years
Projects
- 2 Active
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Application of artificial intelligence in pharmaceutical development
Mourelatou, E. A., Iosif, E., Galatou, E., Sarigiannis, Y., Vlasiou, M. C., Zacharia, L. & Petrou, C. C., 1 Jan 2024, Novel Formulations and Future Trends: Recent and Future Trends in Pharmaceutics, Volume 3. Elsevier, Vol. 3. p. 415-451 37 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review
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Computer-aided drug discovery methods: A brief introduction
Vlasiou, M. C., 11 Oct 2024, Bentham Science Publishers B.V. 150 p.Research output: Book/Report › Book › peer-review
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Editorial: Targeting mitochondrial dysfunction for the diagnosis and treatment of Alzheimer’s and cognitive-related diseases
Vlasiou, M. C., Zacharia, L. C., Douni, E. & Papaneophytou, C., 2024, In: Frontiers in Pharmacology. 15, 1455646.Research output: Contribution to journal › Editorial › peer-review
Open Access -
Staphylococcus epidermidis (Gram +) and Escherichia coli (Gram-) Bacteria Show Sensitivity Against Hymecromone Divalent Transition Metal Complexes of Cobalt and Copper
Panayi, T. & Vlasiou, M. C., 30 Dec 2024, In: Letters in Applied NanoBioScience. 13, 4, 195.Research output: Contribution to journal › Article › peer-review
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Theoretical Studies Revealing Mitochondrial-Targeted Anticancer Activity of Oxovanadium (V) Complexes
Vlasiou, M. C., 30 Dec 2024, In: Letters in Applied NanoBioScience. 13, 4, 174.Research output: Contribution to journal › Article › peer-review