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Research Output 1978 2018

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2018

Quasispecies Changes with Distinctive Point Mutations in the Hepatitis C Virus Internal Ribosome Entry Site (IRES) Derived from PBMCs and Plasma

Mercuri, L., Thomson, E. C., Hughes, J. & Karayiannis, P., 1 Jan 2018, In : Advances in Virology. 2018, 4835252.

Research output: Contribution to journalArticle

Point Mutation
Hepacivirus
Blood Cells
5' Untranslated Regions
Polyproteins
2017
5 Citations (Scopus)

Demographic changes of hepatitis B virus infection in Iran for the last two decades

Shelmani, H. M., Karayiannis, P., Ashtari, S., Mahmanzar, M. A., Khanabadi, B., Modami, N., Gholipour, F., Zare, F. & Zali, M. R., 1 Jan 2017, In : Gastroenterology and Hepatology from Bed to Bench. 10, p. S38-S43

Research output: Contribution to journalArticle

Virus Diseases
Hepatitis B Surface Antigens
Iran
Hepatitis B virus
Demography
13 Citations (Scopus)

Hepatitis B virus: virology, molecular biology, life cycle and intrahepatic spread

Karayiannis, P., 2 Nov 2017, (Accepted/In press) In : Hepatology International. p. 1-9 9 p.

Research output: Contribution to journalArticle

Virology
Life Cycle Stages
Hepatitis B virus
Molecular Biology
Hepadnaviridae
2016
8 Citations (Scopus)

Hepatitis B viral replication influences the expression of natural killer cell ligands

Koumbi, L., Pollicino, T., Raimondo, G., Kumar, N., Karayiannis, P. & Khakoo, S. I., 2016, In : Annals of Gastroenterology. 29, 3, p. 348-357 10 p.

Research output: Contribution to journalArticle

Hepatitis B
Hepatitis B virus
Natural Killer Cells
Ligands
Lectins
5 Citations (Scopus)

Hepatitis B virus basal core promoter mutations show lower replication fitness associated with cccDNA acetylation status

Koumbi, L., Pollicino, T., Raimondo, G., Stampoulis, D., Khakoo, S. & Karayiannis, P., 15 Jul 2016, In : Virus Research. 220, p. 150-160 11 p.

Research output: Contribution to journalArticle

Acetylation
Hepatitis B virus
Mutation
Epigenomics
Histones
2015
1 Citation (Scopus)

Determinants involved in hepatitis C virus and GB virus B primate host restriction

Marnata, C., Saulnier, A., Mompelat, D., Krey, T., Cohen, L., Boukadida, C., Warter, L., Fresquet, J., Vasiliauskaite, I., Escriou, N., Cosset, F. L., Rey, F. A., Lanford, R. E., Karayiannis, P., Rose, N. J., Lavillette, D. & Martin, A., 2015, In : Journal of Virology. 89, 23, p. 12131-12144 14 p.

Research output: Contribution to journalArticle

Hepatitis GB virus B
GB virus B
Hepatitis C virus
Hepacivirus
Primates
2014
1 Citation (Scopus)

Changes in immune cell populations in the periphery and liver of GBV-B-infected and convalescent tamarins (Saguinus labiatus)

Hood, S. P., Mee, E. T., Perkins, H., Bowen, O., Dale, J. M., Almond, N. M., Karayiannis, P., Bright, H., Berry, N. J. & Rose, N. J., 22 Jan 2014, In : Virus Research. 179, 1, p. 93-101 9 p.

Research output: Contribution to journalArticle

26 Citations (Scopus)

HBeaG negative variants and their role in the natural history of chronic hepatitis B virus infection

Alexopoulou, A. & Karayiannis, P., 2014, In : World Journal of Gastroenterology. 20, 24, p. 7644-7652 9 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

HCV NS5A co-operates with PKR in modulating HCV IRES-dependent translation

Karamichali, E., Foka, P., Tsitoura, E., Kalliampakou, K., Kazazi, D., Karayiannis, P., Georgopoulou, U. & Mavromara, P., 2014, In : Infection, Genetics and Evolution. 26, p. 113-122 10 p.

Research output: Contribution to journalArticle

hepatitis
Hepatitis C virus
ribosomes
Hepacivirus
translation (genetics)
2013
23 Citations (Scopus)

Dental treatment as a risk factor for hepatitis B and C viral infection. A review of the recent literature

Mahboobi, N., Porter, S. R., Karayiannis, P. & Alavian, S. M., 2013, In : Journal of Gastrointestinal and Liver Diseases. 22, 1, p. 79-86 8 p.

Research output: Contribution to journalArticle

Virus Diseases
Hepatitis C
Hepatitis B
Hepacivirus
Tooth
2012
23 Citations (Scopus)

Oral fluid and hepatitis A, B and C: A literature review

Mahboobi, N., Porter, S. R., Karayiannis, P. & Alavian, S. M., Aug 2012, In : Journal of Oral Pathology and Medicine. 41, 7, p. 505-516 12 p.

Research output: Contribution to journalArticle

33 Citations (Scopus)

Seroepidemiology of hepatitis A and E virus infections in Tehran, Iran: A population based study

Mohebbi, S. R., Rostami Nejad, M., Tahaei, S. M. E., Pourhoseingholi, M. A., Habibi, M., Azimzadeh, P., Naghoosi, H., Karayiannis, P. & Zali, M. R., Sep 2012, In : Transactions of the Royal Society of Tropical Medicine and Hygiene. 106, 9, p. 528-531 4 p.

Research output: Contribution to journalArticle

Hepatitis E virus
Hepatitis A virus
Virus Diseases
Iran
Population
2011
56 Citations (Scopus)

Hepatitis B surface antigen: Relation to hepatitis B replication parameters in HBeAg-negative chronic hepatitis B

Manesis, E. K., Papatheodoridis, G. V., Tiniakos, D. G., Hadziyannis, E. S., Agelopoulou, O. P., Syminelaki, T., Papaioannou, C., Nastos, T. & Karayiannis, P., Jul 2011, In : Journal of Hepatology. 55, 1, p. 61-68 8 p.

Research output: Contribution to journalArticle

Hepatitis B e Antigens
Chronic Hepatitis B
Hepatitis B Surface Antigens
Hepatitis B
Hepatitis B virus
114 Citations (Scopus)

Predicting spontaneous clearance of acute hepatitis C virus in a large cohort of HIV-1-infected men

Thomson, E. C., Fleming, V. M., Main, J., Klenerman, P., Weber, J., Eliahoo, J., Smith, J., McClure, M. O. & Karayiannis, P., Jun 2011, In : Gut. 60, 6, p. 837-845 9 p.

Research output: Contribution to journalArticle

Hepacivirus
HIV-1
CD4 Lymphocyte Count
T-Lymphocytes
HIV
1 Citation (Scopus)

The detection of hepatitis viruses.

Karayiannis, P., 2011, In : Methods in molecular biology (Clifton, N.J.). 665, p. 79-100 22 p.

Research output: Contribution to journalArticle

2010
28 Citations (Scopus)

Dynamic coinfection with multiple viral subtypes in acute hepatitis C

Smith, J. A., Aberle, J. H., Fleming, V. M., Ferenci, P., Thomson, E. C., Karayiannis, P., McLean, A. R., Holzmann, H. & Klenerman, P., 15 Dec 2010, In : Journal of Infectious Diseases. 202, 12, p. 1770-1779 10 p.

Research output: Contribution to journalArticle

Hepatitis C
Coinfection
Hepacivirus
Virus Diseases
Viral Load
13 Citations (Scopus)
alpha-Fetoproteins
Hepatitis B virus
Antiviral Agents
Hepatocellular Carcinoma
Therapeutics
35 Citations (Scopus)

Steatosis and steatohepatitis in postmortem material from Northwestern Greece

Zois, C. D., Baltayiannis, G. H., Bekiari, A., Goussia, A., Karayiannis, P., Doukas, M., Demopoulos, D., Mitsellou, A., Vougiouklakis, T., Mitsi, V. & Tsianos, E. V., 21 Aug 2010, In : World Journal of Gastroenterology. 16, 31, p. 3944-3949 6 p.

Research output: Contribution to journalArticle

Greece
Fatty Liver
Cause of Death
Autopsy
Liver
2009
13 Citations (Scopus)

Core mutations in patients with acute episodes of chronic HBV infection are associated with the emergence of new immune recognition sites and the development of high IgM Anti-HBc index values

Alexopoulou, A., Baltayiannis, G., Eroglu, C., Nastos, T., Dourakis, S. P., Archimandritis, A. J. & Karayiannis, P., Jan 2009, In : Journal of Medical Virology. 81, 1, p. 34-41 8 p.

Research output: Contribution to journalArticle

Hepatitis B e Antigens
Chronic Hepatitis B
Virus Diseases
Hepatitis B virus
B-Lymphocyte Epitopes
122 Citations (Scopus)

Delayed anti-HCV antibody response in HIV-positive men acutely infected with HCV

Thomson, E. C., Nastouli, E., Main, J., Karayiannis, P., Eliahoo, J., Muir, D. & McClure, M. O., 2 Jan 2009, In : AIDS. 23, 1, p. 89-93 5 p.

Research output: Contribution to journalArticle

Hepatitis C Antibodies
Hepacivirus
Antibody Formation
HIV
Virus Diseases
10 Citations (Scopus)

Diagnosing acute hepatitis C in HIV-infected patients: Nucleic acid testing compared with antibody and antigen-antibody detecting methods

Nastouli, E., Thomson, E. C., Karayiannis, P., Main, J., McClure, M. & Muir, D., Jan 2009, In : Journal of Clinical Virology. 44, 1, p. 78-80 3 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Long-term outcome of hepatitis B and hepatitis C virus co-infection and single HBV infection acquired in youth

Zampino, R., Marrone, A., Merola, A., Trani, B., Cirillo, G., Karayiannis, P., Coppola, N., Zappalà, R., Utili, R., Ruggiero, G. & Adinolfi, L. E., Dec 2009, In : Journal of Medical Virology. 81, 12, p. 2012-2020 9 p.

Research output: Contribution to journalArticle

Virus Diseases
Hepatitis B
Coinfection
Hepacivirus
Infection
2008
87 Citations (Scopus)

Effect of basal core promoter and pre-core mutations on hepatitis B virus replication

Jammeh, S., Tavner, F., Watson, R., Thomas, H. C. & Karayiannis, P., Apr 2008, In : Journal of General Virology. 89, 4, p. 901-909 9 p.

Research output: Contribution to journalArticle

Virus Replication
Hepatitis B virus
Hepatitis B e Antigens
Mutation
Genetic Promoter Regions
4 Citations (Scopus)

Restricted quasispecies variation following infection with the GB virus B

McGarvey, M. J., Iqbal, M., Nastos, T. & Karayiannis, P., Jul 2008, In : Virus Research. 135, 1, p. 181-186 6 p.

Research output: Contribution to journalArticle

GB virus B
Infection
5' Untranslated Regions
Amino Acid Substitution
Hepacivirus
7 Citations (Scopus)

Tailored regimen of interferon alpha for HBeAg-positive chronic hepatitis B: A prospective controlled study

Luo, K., Mao, Q., Karayiannis, P., Liu, D., Liu, Z., Zhou, Y., Feng, X., Zhu, Y., Guo, Y., Jiang, R., Zhou, F., Peng, J. & Hou, J., Sep 2008, In : Journal of Viral Hepatitis. 15, 9, p. 684-689 6 p.

Research output: Contribution to journalArticle

2007
9 Citations (Scopus)

Replicative competence of the T131I, K141E, and G145R surface variants of hepatitis B virus

Jammeh, S., Thomas, H. C. & Karayiannis, P., 2007, In : Journal of Infectious Diseases. 196, 7, p. 1010-1013 4 p.

Research output: Contribution to journalArticle

Hepatitis B virus
Mental Competency
Satellite Viruses
DNA
Amino Acid Substitution
2006
11 Citations (Scopus)

Detection of a hepatitis B surface antigen variant emerging in a patient with chronic lymphocytic leukaemia treated with fludarabine

Alexopoulou, A., Dourakis, S. P., Pandelidaki, H., Archimandritis, A. J. & Karayiannis, P., Aug 2006, In : Journal of Medical Virology. 78, 8, p. 1043-1046 4 p.

Research output: Contribution to journalArticle

B-Cell Chronic Lymphocytic Leukemia
Hepatitis B Surface Antigens
Hepatitis B virus
Hepatitis B e Antigens
DNA
24 Citations (Scopus)

Hepatitis B virus reactivation in patients receiving chemotherapy for malignancies: Role of precore stop-codon and basic core promoter mutations

Alexopoulou, A., Theodorou, M., Dourakis, S. P., Karayiannis, P., Sagkana, E., Papanikolopoulos, K. & Archimandritis, A. J., Sep 2006, In : Journal of Viral Hepatitis. 13, 9, p. 591-596 6 p.

Research output: Contribution to journalArticle

Terminator Codon
Hepatitis B virus
Hepatitis B Surface Antigens
Hepatitis B e Antigens
Drug Therapy
2 Citations (Scopus)

Interferon-α therapy in HBeAg-negative chronic hepatitis B: A long-term prospective study from north-western Greece

Baltayiannis, G., Katsanos, K., Karayiannis, P. & Tsianos, E. V., Aug 2006, In : Alimentary Pharmacology and Therapeutics. 24, 3, p. 525-533 9 p.

Research output: Contribution to journalArticle

Hepatitis B e Antigens
Greece
Chronic Hepatitis B
Interferons
Prospective Studies
2005
8 Citations (Scopus)

Clinical reactivation during lamivudine treatment correlates with mutations in the precore/core promoter and polymerase regions of hepatitis B virus in patients with anti-hepatitis B e-positive chronic hepatitis

Marrone, A., Zampino, R., Karayannis, P., Cirillo, G., Cesaro, G., Guerrera, B., Ricciotti, R., Miraglia Del Giudice, E., Utili, R., Adinolfi, L. E. & Ruggiero, G., 15 Oct 2005, In : Alimentary Pharmacology and Therapeutics. 22, 8, p. 707-714 8 p.

Research output: Contribution to journalArticle

Lamivudine
Chronic Hepatitis
Hepatitis B
Genetic Promoter Regions
Hepatitis B virus
11 Citations (Scopus)

Heart transplantation in patients with chronic hepatitis B: Clinical evolution, molecular analysis, and effect of treatment

Zampino, R., Marrone, A., Ragone, E., Costagliola, L., Cirillo, G., Karayiannis, P., Ruggiero, G. & Utili, R., Nov 2005, In : Transplantation. 80, 9, p. 1340-1343 4 p.

Research output: Contribution to journalArticle

2004
20 Citations (Scopus)

Comparison of Hepatitis C Viral Loads in Patients with or without Coinfection with Different Genotypes

Schijman, A., Colina, R., Mukomolov, S., Kalinina, O., García, L., Broor, S., Bhupatiraju, A. V., Karayiannis, P., Khan, B., Mogdasy, C. & Cristina, J., Mar 2004, In : Clinical and Diagnostic Laboratory Immunology. 11, 2, p. 433-435 3 p.

Research output: Contribution to journalArticle

Hepatitis C
Viral Load
Coinfection
Viruses
Genotype
16 Citations (Scopus)

Hepatitis B surface antigen variant with multiple mutations in the a determinant in an agammaglobulinemic patient

Alexopoulou, A., Baltayiannis, G., Jammeh, S., Waters, J., Dourakis, S. P. & Karayiannis, P., Jun 2004, In : Journal of Clinical Microbiology. 42, 6, p. 2861-2865 5 p.

Research output: Contribution to journalArticle

Hepatitis B Surface Antigens
Agammaglobulinemia
Mutation
Amino Acid Substitution
Hepatitis B virus
191 Citations (Scopus)

Identification of Unique Hepatitis C Virus Quasispecies in the Central Nervous System and Comparative Analysis of Internal Translational Efficiency of Brain, Liver, and Serum Variants

Forton, D. M., Karayiannis, P., Mahmud, N., Taylor-Robinson, S. D. & Thomas, H. C., May 2004, In : Journal of Virology. 78, 10, p. 5170-5183 14 p.

Research output: Contribution to journalArticle

Hepatitis C virus
Hepacivirus
central nervous system
Central Nervous System
brain
2003
45 Citations (Scopus)

An outbreak of HBV and HCV infection in a paediatric oncology ward: Epidemiological investigations and prevention of further spread

Dumpis, U., Kovaļova, Ž., Jansons, J., Čupane, L., Sominskaya, I., Michailova, M., Karayiannis, P., Gardovska, D., Viazov, S., Ross, S., Roggendorf, M. & Pumpens, P., 1 Mar 2003, In : Journal of Medical Virology. 69, 3, p. 331-338 8 p.

Research output: Contribution to journalArticle

Virus Diseases
Disease Outbreaks
Pediatrics
Viruses
RNA Viruses
26 Citations (Scopus)

Changes in hypervariable region 1 of the envelope 2 glycoprotein of hepatitis C virus in children and adults with humoral immune defects

Gaud, U., Langer, B., Petropoulou, T., Thomas, H. C. & Karayiannis, P., 1 Mar 2003, In : Journal of Medical Virology. 69, 3, p. 350-356 7 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)

Hepatitis C virus E2 and NS5A region variability during sequential treatment with two interferon-α preparations

Durante Mangoni, E., Forton, D. M., Ruggiero, G. & Karayiannis, P., 1 May 2003, In : Journal of Medical Virology. 70, 1, p. 62-73 12 p.

Research output: Contribution to journalArticle

Hepacivirus
Interferons
Interferon-alpha
Therapeutics
Amino Acids
18 Citations (Scopus)

Low HBeAg serum levels correlate with the presence of the double A1762T/G1764A core promoter mutation and a positive response to interferon in patients with chronic hepatitis B virus infection

Marrone, A., Zampino, R., Luongo, G., Utili, R., Karayiannis, P. & Ruggiero, G., 2003, In : Intervirology. 46, 4, p. 222-226 5 p.

Research output: Contribution to journalArticle

Hepatitis B e Antigens
Chronic Hepatitis B
Virus Diseases
Hepatitis B virus
Interferons
2002
5 Citations (Scopus)

Core promoter mutations 3 years after anti-hepatitis B e seroconversion in patients with chronic hepatitis B or hepatitis B and C infection and cancer remission

Zampino, R., Marrone, A., Karayiannis, P., Cirillo, G., Miraglia del Giudice, E., Rania, G., Utili, R. & Ruggiero, G., 2002, In : American Journal of Gastroenterology. 97, 9, p. 2426-2431 6 p.

Research output: Contribution to journalArticle

Chronic Hepatitis B
Hepatitis C
Hepatitis B
Hepatitis B virus
Mutation

Core promoter mutations 3 years after anti-hepatitis B e seroconversion in patients with chronic hepatitis B or hepatitis B and C infection and cancer remission

Zampino, R., Marrone, A., Karayiannis, P., Cirillo, G., Del Giudice, E. M., Rania, G., Utili, R. & Ruggiero, G., 2002, In : American Journal of Gastroenterology. 97, 9, p. 2426-2431 6 p., 5998.

Research output: Contribution to journalArticle

38 Citations (Scopus)

Detection and significance of a G1862T variant of hepatitis B virus in Chinese patients with fulminant hepatitis

Hou, J., Lin, Y., Waters, J., Wang, Z., Min, J., Liao, H., Jiang, J., Chen, J., Luo, K. & Karayiannis, P., Sep 2002, In : Journal of General Virology. 83, 9, p. 2291-2298 8 p.

Research output: Contribution to journalArticle

Hepatitis B virus
Hepatitis
Hepatitis B e Antigens
Mutation
Protein Precursors
3 Citations (Scopus)

Hepatitis C virus phylogeny: A useful clinical tool

Cristina, J., Mukomolov, S., Colina, R., Kalinina, O., García, L., Khan, B., Mogdasy, C. & Karayiannis, P., 2002, In : Acta Virologica. 46, 3, p. 179-182 4 p.

Research output: Contribution to journalArticle

Phylogeny
Hepacivirus
Genome
Viruses
Costs and Cost Analysis
29 Citations (Scopus)

Intra-familial transmission of hepatitis B virus in Italy: Phylogenetic sequence analysis and amino-acid variation of the core gene

Zampino, R., Lobello, S., Chiaramonte, M., Venturi-Pasini, C., Dumpis, U., Thursz, M. & Karayiannis, P., 2002, In : Journal of Hepatology. 36, 2, p. 248-253 6 p.

Research output: Contribution to journalArticle

Protein Sequence Analysis
Hepatitis B virus
Italy
Viruses
Genes
20 Citations (Scopus)

Sequential analysis of hepatitis B virus core promoter and precore regions in cancer survivor patients with chronic hepatitis B before, during and after interferon treatment

Zampino, R., Marrone, A., Cirillo, G., Del Giudice, E. M., Utili, R., Karayiannis, P., Liang, T. J. & Ruggiero, G., 2002, In : Journal of Viral Hepatitis. 9, 3, p. 183-188 6 p.

Research output: Contribution to journalArticle

Chronic Hepatitis B
Genetic Promoter Regions
Hepatitis B virus
Interferons
Survivors
2001
34 Citations (Scopus)

Hepatitis B surface antigen variants in vaccinees, blood donors and an interferon-treated patient

Seddigh-Tonekaboni, S., Lim, W. L., Young, B., Hou, J. L., Waters, J., Luo, K. X., Thomas, H. C. & Karayiannis, P., 2001, In : Journal of Viral Hepatitis. 8, 2, p. 154-158 5 p.

Research output: Contribution to journalArticle

Hepatitis B Surface Antigens
Blood Donors
Interferons
Amino Acid Substitution
Hepatitis B virus
25 Citations (Scopus)

Prevalence of HBV core promoter/precore/core mutations in Gambian chronic carriers

Dumpis, U., Mendy, M., Hill, A., Thursz, M., Hall, A., Whittle, H. & Karayiannis, P., 2001, In : Journal of Medical Virology. 65, 4, p. 664-670 7 p.

Research output: Contribution to journalArticle

Hepatitis B e Antigens
Hepatitis B virus
Mutation
Terminator Codon
Chronic Hepatitis B
149 Citations (Scopus)

Prevalence of naturally occurring surface gene variants of hepatitis B virus in nonimmunized surface antigen-Negative Chinese carriers

Hou, J., Wang, Z., Cheng, J., Lin, Y., Lau, G. K. K., Sun, J., Zhou, F., Waters, J., Karayiannis, P. & Luo, K., 2001, In : Hepatology. 34, 5, p. 1027-1034 8 p.

Research output: Contribution to journalArticle

Surface Antigens
Hepatitis B virus
Hepatitis B Surface Antigens
Genes
Virus Diseases
7 Citations (Scopus)

Purification of woodchuck hepatitis surface antigen using a monoclonal antibody raised against the antigen

Waters, J. A., O'Neill, C., Abdul-Gader, A., Goldin, R., Karayiannis, P. & Monjardino, J., 2001, In : Journal of Virological Methods. 93, 1-2, p. 97-103 7 p.

Research output: Contribution to journalArticle

Hepatitis Antigens
Marmota
Woodchuck Hepatitis B Virus
Surface Antigens
Virus Diseases
3 Citations (Scopus)

Reactivation of precore variant hepatitis B virus in a child with severe aplastic anaemia

Smith, P. R., Zampino, R., Gutteridge, C., Karayiannis, P. & Aitken, C., 2001, In : Journal of Medical Virology. 65, 3, p. 470-472 3 p.

Research output: Contribution to journalArticle

Aplastic Anemia
Hepatitis B virus
A 1899
Hepatitis B Antibodies
Hepatitis B e Antigens
79 Citations (Scopus)

Transmission of hepatitis B virus infection in Gambian families revealed by phylogenetic analysis

Dumpis, U., Holmes, E. C., Mendy, M., Hill, A., Thursz, M., Hall, A., Whittle, H. & Karayiannis, P., 2001, In : Journal of Hepatology. 35, 1, p. 99-104 6 p.

Research output: Contribution to journalArticle

Virus Diseases
Hepatitis B virus
Sequence Analysis
Gambia
Conserved Sequence