Theodoros Kyriakides

1988 …2017

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2017

C1q ablation exacerbates amyloid deposition: A study in a transgenic mouse model of ATTRV30M amyloid neuropathy

Panayiotou, E., Fella, E., Papacharalambous, R., Malas, S., Saraiva, M. J. & Kyriakides, T., 1 Apr 2017, In : PLoS ONE. 12, 4, e0175767.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Epidemiology of Amyotrophic Lateral Sclerosis in the Republic of Cyprus: A 25-Year Retrospective Study

Demetriou, C. A., Hadjivasiliou, P. M., Kleopa, K. A., Christou, Y. P., Leonidou, E., Kyriakides, T. & Zamba-Papanicolaou, E., 1 Jun 2017, In : Neuroepidemiology. 48, 1-2, p. 79-85 7 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Gene variants of adhesion molecules act as modifiers of disease severity in MS

Dardiotis, E., Panayiotou, E., Provatas, A., Christodoulou, K., Hadjisavvas, A., Antoniades, A., Lourbopoulos, A., Pantzaris, M., Grigoriadis, N., Hadjigeorgiou, G. M. & Kyriakides, T., 2017, In : Neurology: Neuroimmunology and NeuroInflammation. 4, 4

Research output: Contribution to journalArticle

11 Citations (Scopus)

Pharmacological stimulation of phagocytosis enhances amyloid plaque clearance; evidence from a transgenic mouse model of ATTR neuropathy

Fella, E., Sokratous, K., Papacharalambous, R., Kyriacou, K., Phillips, J., Sanderson, S., Panayiotou, E. & Kyriakides, T., 10 May 2017, In : Frontiers in Molecular Neuroscience. 10, 138.

Research output: Contribution to journalArticle

2 Citations (Scopus)
2016

Genetic background modifies amyloidosis in a mouse model of ATTR neuropathy

Panayiotou, E., Papacharalambous, R., Antoniou, A., Christophides, G., Papageorgiou, L., Fella, E., Malas, S. & Kyriakides, T., 1 Dec 2016, In : Biochemistry and Biophysics Reports. 8, p. 48-54 7 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Recommendations for presymptomatic genetic testing and management of individuals at risk for hereditary transthyretin amyloidosis

Obici, L., Kuks, J. B., Buades, J., Adams, D., Suhr, O. B., Coelho, T., Kyriakides, T. & from the European Network for TTR-FAP (ATTReuNET), 5 Jan 2016, (Accepted/In press) In : Current Opinion in Neurology.

Research output: Contribution to journalArticle

44 Citations (Scopus)

Titin antibodies in "seronegative" myasthenia gravis - A new role for an old antigen

Stergiou, C., Lazaridis, K., Zouvelou, V., Tzartos, J., Mantegazza, R., Antozzi, C., Andreetta, F., Evoli, A., Deymeer, F., Saruhan-Direskeneli, G., Durmus, H., Brenner, T., Vaknin, A., Berrih-Aknin, S., Behin, A., Sharshar, T., De Baets, M., Losen, M., Martinez-Martinez, P., Kleopa, K. A. & 19 others, Zamba-Papanicolaou, E., Kyriakides, T., Kostera-Pruszczyk, A., Szczudlik, P., Szyluk, B., Lavrnic, D., Basta, I., Peric, S., Tallaksen, C., Maniaol, A., Gilhus, N. E., Casasnovas Pons, C., Pitha, J., Jakubíkova, M., Hanisch, F., Bogomolovas, J., Labeit, D., Labeit, S. & Tzartos, S. J., 15 Mar 2016, In : Journal of Neuroimmunology. 292, p. 108-115 8 p.

Research output: Contribution to journalArticle

26 Citations (Scopus)
2015

Genetic findings of Cypriot spinal muscular atrophy patients

Theodorou, L., Nicolaou, P., Koutsou, P., Georghiou, A., Anastasiadou, V., Tanteles, G., Kyriakides, T., Zamba-Papanicolaou, E. & Christodoulou, K., 30 Oct 2015, In : Neurological Sciences. 36, 10, p. 1829-1834 6 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Minimally symptomatic mcardle disease, expanding the genotype-phenotype spectrum

Petrou, P., Pantzaris, M., Dionysiou, M., Drousiotou, A. & Kyriakides, T., 1 Nov 2015, In : Muscle and Nerve. 52, 5, p. 891-895 5 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

MuSK autoantibodies in myasthenia gravis detected by cell based assay - A multinational study

Tsonis, A. I., Zisimopoulou, P., Lazaridis, K., Tzartos, J., Matsigkou, E., Zouvelou, V., Mantegazza, R., Antozzi, C., Andreetta, F., Evoli, A., Deymeer, F., Saruhan-Direskeneli, G., Durmus, H., Brenner, T., Vaknin, A., Berrih-Aknin, S., Behin, A., Sharshar, T., De Baets, M., Losen, M. & 17 others, Martinez-Martinez, P., Kleopa, K. A., Zamba-Papanicolaou, E., Kyriakides, T., Kostera-Pruszczyk, A., Szczudlik, P., Szyluk, B., Lavrnic, D., Basta, I., Peric, S., Tallaksen, C., Maniaol, A., Casasnovas Pons, C., Pitha, J., Jakubíkova, M., Hanisch, F. & Tzartos, S. J., 15 Jul 2015, In : Journal of Neuroimmunology. 284, p. 10-17 8 p.

Research output: Contribution to journalArticle

36 Citations (Scopus)
2014

A comprehensive analysis of the epidemiology and clinical characteristics of anti-LRP4 in myasthenia gravis

Zisimopoulou, P., Evangelakou, P., Tzartos, J., Lazaridis, K., Zouvelou, V., Mantegazza, R., Antozzi, C., Andreetta, F., Evoli, A., Deymeer, F., Saruhan-Direskeneli, G., Durmus, H., Brenner, T., Vaknin, A., Berrih-Aknin, S., Frenkian Cuvelier, M., Stojkovic, T., DeBaets, M., Losen, M., Martinez-Martinez, P. & 12 others, Kleopa, K. A., Zamba-Papanicolaou, E., Kyriakides, T., Kostera-Pruszczyk, A., Szczudlik, P., Szyluk, B., Lavrnic, D., Basta, I., Peric, S., Tallaksen, C., Maniaol, A. & Tzartos, S. J., 2014, In : Journal of Autoimmunity. 52, p. 139-145 7 p.

Research output: Contribution to journalArticle

138 Citations (Scopus)

Cervical vestibular evoked myogenic potentials in cerebellar lesions

Papacostas, S. S., Papathanasiou, E. S., Kyriakides, T. & Pantzaris, M., 2014, In : Otology and Neurotology. 35, 9, p. 1633-1637 5 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
2013

Effect of exercise training and dopamine agonists in patients with uremic restless legs syndrome: A six-month randomized, partially double-blind, placebo-controlled comparative study

Giannaki, C. D., Sakkas, G. K., Karatzaferi, C., Hadjigeorgiou, G. M., Lavdas, E., Kyriakides, T., Koutedakis, Y. & Stefanidis, I., 2013, In : BMC Nephrology. 14, 1, 194.

Research output: Contribution to journalArticle

57 Citations (Scopus)

EFNS review on the role of muscle biopsy in the investigation of myalgia

Kyriakides, T., Angelini, C., Schaefer, J., Mongini, T., Siciliano, G., Sacconi, S., Joseph, J., Burgunder, J. M., Bindoff, L. A., Vissing, J., De Visser, M. & Hilton-Jones, D., Jul 2013, In : European Journal of Neurology. 20, 7, p. 997-1005 9 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)

How does fingolimod (gilenya®) fit in the treatment algorithm for highly active relapsing-remitting multiple sclerosis?

Fazekas, F., Bajenaru, O., Berger, T., Fabjan, T. H., Ledinek, A. H., Jakab, G., Komoly, S., Kobys, T., Kraus, J., Kurča, E., Kyriakides, T., Lisý, L., Milanov, I., Nehrych, T., Moskovko, S., Panayiotou, P., Jazbec, S. Š., Sokolova, L., Taláb, R., Traykov, L. & 5 others, Turčáni, P., Vass, K., Vella, N., Voloshyná, N. & Havrdová, E., 2013, In : Frontiers in Neurology. 4 MAY, 10.

Research output: Contribution to journalArticle

18 Citations (Scopus)

Intraperitoneal melatonin is not neuroprotective in the G93ASOD1 transgenic mouse model of familial ALS and may exacerbate neurodegeneration

Dardiotis, E., Panayiotou, E., Feldman, M. L., Hadjisavvas, A., Malas, S., Vonta, I., Hadjigeorgiou, G., Kyriakou, K. & Kyriakides, T., 26 Aug 2013, In : Neuroscience Letters. 548, p. 170-175 6 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)
2012

Investigation of SCA10 in the Cypriot population: Further exclusion of SCA dynamic repeat mutations

Votsi, C., Zamba-Papanicolaou, E., Georghiou, A., Kyriakides, T., Papacostas, S., Kleopa, K. A., Pantzaris, M. & Christodoulou, K., 15 Dec 2012, In : Journal of the Neurological Sciences. 323, 1-2, p. 154-157 4 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Multi-scale AM-FM analysis for the classification of surface electromyographic signals

Christodoulou, C. I., Kaplanis, P. A., Murray, V., Pattichis, M. S., Pattichis, C. S. & Kyriakides, T., May 2012, In : Biomedical Signal Processing and Control. 7, 3, p. 265-269 5 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)
2011

A correlative study of quantitative EMG and biopsy findings in 31 patients with myopathies

Dardiotis, E., Papathanasiou, E., Vonta, I., Hadjigeorgiou, G., Zamba-Papanicolaou, E. & Kyriakides, T., Jun 2011, In : Acta Myologica. 30, JUNE, p. 37-41 5 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

An unusual case of suprascapular nerve neuropathy: A case report

Economides, C. P., Christodoulou, L., Kyriakides, T. & Soteriades, E. S., 2011, In : Journal of Medical Case Reports. 5, 419.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Sleep hypoventilation syndrome and respiratory failure due to multifocal motor neuropathy with conduction block

Kyriakides, T., Papacostas, S., Papanicolaou, E., Bagdades, E. & Papathanasiou, E. S., Apr 2011, In : Muscle and Nerve. 43, 4, p. 610-614 5 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)
2010

Charcot-marie-tooth disease in Cyprus: Epidemiological, clinical and genetic characteristics

Nicolaou, P., Zamba-Papanicolaou, E., Koutsou, P., Kleopa, K. A., Georghiou, A., Hadjigeorgiou, G., Papadimitriou, A., Kyriakides, T. & Christodoulou, K., Oct 2010, In : Neuroepidemiology. 35, 3, p. 171-177 7 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)
2009

Complement C1Q polymorphisms modulate onset in familial amyloidotic polyneuropathy TTR Val30Met

Dardiotis, E., Koutsou, P., Zamba-Papanicolaou, E., Vonta, I., Hadjivassiliou, M., Hadjigeorgiou, G., Cariolou, M., Christodoulou, K. & Kyriakides, T., 15 Sep 2009, In : Journal of the Neurological Sciences. 284, 1-2, p. 158-162 5 p.

Research output: Contribution to journalArticle

26 Citations (Scopus)

Epidemiological, clinical and genetic study of familial amyloidotic polyneuropathy in Cyprus

Dardiotis, E., Koutsou, P., Papanicolaou, E. Z., Vonta, I., Kladi, A., Vassilopoulos, D., Hadjigeorgiou, G., Christodoulou, K. & Kyriakides, T., Mar 2009, In : Amyloid. 16, 1, p. 32-37 6 p.

Research output: Contribution to journalArticle

28 Citations (Scopus)
2008

Ten-year mortality from Creutzfeldt-Jakob disease in Cyprus

Papacostas, S., Malikides, A., Petsa, M. & Kyriakides, T., May 2008, In : Eastern Mediterranean Health Journal. 14, 3, p. 715-719 5 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)
2007

Differential expression of molecular motors in the motor cortex of sporadic ALS

Pantelidou, M., Zographos, S. E., Lederer, C. W., Kyriakides, T., Pfaffl, M. W. & Santama, N., Jun 2007, In : Neurobiology of Disease. 26, 3, p. 577-589 13 p.

Research output: Contribution to journalArticle

34 Citations (Scopus)
19 Citations (Scopus)
2006
7 Citations (Scopus)

Naturally occurring utrophin correlates with disease severity in Duchenne muscular dystrophy

Kleopa, K. A., Drousiotou, A., Mavrikiou, E., Ormiston, A. & Kyriakides, T., 15 May 2006, In : Human Molecular Genetics. 15, 10, p. 1623-1628 6 p.

Research output: Contribution to journalArticle

52 Citations (Scopus)

Phenotypic and cellular expression of two novel connexin32 mutations causing CMT1X

Kleopa, K. A., Zamba-Papanicolaou, E., Alevra, X., Nicolaou, P., Georgiou, D. M., Hadjisavvas, A., Kyriakides, T. & Christodoulou, K., Feb 2006, In : Neurology. 66, 3, p. 396-402 7 p.

Research output: Contribution to journalArticle

42 Citations (Scopus)
2005

Morphological methods in the diagnosis of mitochondrial encephalomyopathies: The role of electron microscopy

Kyriacou, K., Hadjisavvas, A., Zenios, A., Papacharalambous, R. & Kyriakides, T., May 2005, In : Ultrastructural Pathology. 29, 3-4, p. 169-174 6 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Neurogenic vestibular evoked potentials in three cases of vestibular system dysfunction

Papathanasiou, E. S., Piperidou, C., Iliopoulos, I., Malekidou, A., Katelari-Theocharidou, E., Kyriakides, T., Kleopa, K. A. & Papacostas, S. S., Jan 2005, In : Electromyography and Clinical Neurophysiology. 45, 1, p. 39-45 7 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Phenotypic spectrum of disorders associated with glycyl-tRNA synthetase mutations

Sivakumar, K., Kyriakides, T., Puls, I., Nicholson, G. A., Funalot, B., Antonellis, A., Sambuughin, N., Christodoulou, K., Beggs, J. L., Zamba-Papanicolaou, E., Ionasescu, V., Dalakas, M. C., Green, E. D., Fischbeck, K. H. & Goldfarb, L. G., Oct 2005, In : Brain. 128, 10, p. 2304-2314 11 p.

Research output: Contribution to journalArticle

97 Citations (Scopus)

Reversible inflammatory and vacuolar myopathy with vitamin E deficiency in celiac disease

Kleopa, K. A., Kyriacou, K., Zamba-Papanicolaou, E. & Kyriakides, T., Feb 2005, In : Muscle and Nerve. 31, 2, p. 260-265 6 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)

Vestibular symptoms and signs are correlated with abnormal neurogenic vestibular evoked potentials in patients with multiple sclerosis

Papathanasiou, E. S., Piperidou, C., Pantzaris, M., Iliopoulos, I., Petsa, M., Kyriakides, T., Kleopa, K. A. & Papacostas, S. S., Jun 2005, In : Electromyography and Clinical Neurophysiology. 45, 4, p. 195-201 7 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)
2004

A novel movement disorder of the lower lip

Kleopas, K. A. & Kyriakides, T., Jun 2004, In : Movement Disorders. 19, 6, p. 663-704 42 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

A novel PMP22 mutation Ser22Phe in a family with hereditary neuropathy with liability to pressure palsies and CMT1A phenotypes

Kleopa, K. A., Georgiou, D. M., Nicolaou, P., Koutsou, P., Papathanasiou, E., Kyriakides, T. & Christodoulou, K., Sep 2004, In : Neurogenetics. 5, 3, p. 171-175 5 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Neurogenic vestibular evoked potentials in the diagnosis of multiple sclerosis

Papathanasiou, E. S., Pantzaris, M., Zamba-Papanicolaou, E., Kyriakides, T., Kleopa, K. A., Iliopoulos, I., Piperidou, C. & Papacostas, S., Jul 2004, In : Electromyography and Clinical Neurophysiology. 44, 5, p. 313-317 5 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Neurogenic vestibular evoked potentials using a tone pip auditory stimulus

Papathanasiou, E. S., Zamba-Papanicolaou, E., Pantziaris, M., Kleopas, K., Kyriakides, T., Papacostas, S., Pattichis, C., Iliopoulos, I. & Piperidou, C., Mar 2004, In : Electromyography and Clinical Neurophysiology. 44, 3, p. 167-173 7 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)
2003

A comparative morphological study in 33 cases of respiratory chain encephalomyopathies

Kyriakides, T., Drousiotou, A., Panasopoulou, A., Hadjisavvas, A., Zenios, A., Hadjigeorgiou, G. M. & Kyriacou, K., Sep 2003, In : Acta Myologica. 22, SEPT., p. 48-51 4 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Click evoked neurogenic vestibular potentials (NVESTEPs): A method of assessing the function of the vestibular system

Papathanasiou, E. S., Zamba-Papanicolaou, E., Pantziaris, M., Kyriakides, T., Papacostas, S., Myrianthopoulou, P., Pattichis, C., Iliopoulos, I. & Piperidou, C., Oct 2003, In : Electromyography and Clinical Neurophysiology. 43, 7, p. 399-408 10 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Compressive lumbar myelopathy presenting as segmental motor neuron disease

Kleopa, K. A., Zamba-Papanicolaou, E. & Kyriakides, T., 1 Jul 2003, In : Muscle and Nerve. 28, 1, p. 69-73 5 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)
2002

Amyloid myopathy: Evidence for mechanical injury to the sarcolemma

Kyriakides, T., Marquez, B., Panousopoulos, A., Kyriacou, E. & Kyriacou, K., 2002, In : Clinical Neuropathology. 21, 4, p. 145-148 4 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

A novel NF-L mutation pro22ser is associated with CMT2 in a large Slovenian family

Georgiou, D. M., Zidar, J., Korošec, M., Middleton, L. T., Kyriakides, T. & Christodoulou, K., Oct 2002, In : Neurogenetics. 4, 2, p. 93-96 4 p.

Research output: Contribution to journalArticle

81 Citations (Scopus)

Hereditary motor neuronopathies

Zamba-Papanicolaou, E., Christodoulou, K., Christodoulou, C., Kyriakides, T. & Middleton, L. T., 1 Dec 2002, In : Revue Neurologique. 158, 12 I, p. 1220-1224 5 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)
2001

Autosomal recessive distal hereditary motor neuropathies

Zamba, E., Christodoulou, K., Al-Qudah, A. K., Horani, K., Kyriakides, T., Middleton, L. T. & Mubaidin, A., 2001, In : Acta Myologica. 20, MAY, p. 53-56 4 p.

Research output: Contribution to journalArticle

Editorial

Vance, J. M., Middleton, L. T., Christodoulou, K., Georghiou, D. M., Kyriakides, T., Zamba, E., Guilbot, A., I-Petrusewicz, H., Ben Hamida, C., Ben Hamida, M., Hentati, F., Mubaidin, A., Ozdemir, C., Serdaroglu, P., Sevilla, T., Vilchez, J. J., Beyer, A. L., Fetterolf, A., Krajewski, K., Shy, M. & 5 others, De Jonghe, P., Timmerman, V., Politano, L., Tonali, P. & Zidar, J., 2001, In : Acta Myologica. 20, MAY, p. 1-3 3 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Molecular genetic studies in autosomal recessive Charcot-Marie-Tooth disease

Georgiou, D. M., Jedrzejowska, H., Ryniewicz, B., Hausmanowa-Petrusewicz, I., Zamba, E., Kyriakides, T., Christodoulou, K. & Middleton, L. T., 2001, In : Acta Myologica. 20, MAY, p. 35-38 4 p.

Research output: Contribution to journalArticle

2000

A novel form of distal hereditary motor neuronopathy maps to chromosome 9p21.1-p12

Christodoulou, K., Zamba, E., Tsingis, M., Mubaidin, A., Horani, K., Abu-Sheik, S., El-Khateeb, M., Kyriacou, K., Kyriakides, T., Al-Qudah, A. K. & Middleton, L., 2000, In : Annals of Neurology. 48, 6, p. 877-884 8 p.

Research output: Contribution to journalArticle

1999

A comparative study of the sensitivity and specificity of morphological methods and biochemical assay in diagnosing 17 cases of respiratory chain encephalomyopathies

Kyriakides, T., Panasopoulos, A., Mavrikiou, E., Hadjianastasiou, A., Mikellidou, C., Drousiotou, A. & Kyriacou, K., 1999, In : Acta Myologica. 3, p. 76 1 p.

Research output: Contribution to journalArticle