Stage at diagnosis (TSD) and cancer survival in Cyprus: A population-based study of patients diagnosed with breast, cervical, colorectal, lung, prostate and thyroid cancer between 2004 and 2017

Project: Research

Project Details

Description

Tumor Stage at Diagnosis (TSD) is a key piece of information in:
• predicting patients’ prognosis and survival
• informing treatment decisions
• planning the provision of cancer-related resources and services
• assessing the effectiveness of public health interventions

Evaluation of the distribution of stage at diagnosis and the survival trends by stage at diagnosis helps to assess the intensity of diagnostic activity in a given country or region and to determine the effectiveness of the health system in offering optimal stage-specific treatment to patients.
In order to provide a better understanding of the cancer profile and cancer survival by TSD in the country, our study aims:

• to assess the distribution of stage at diagnosis in Cyprus for breast, cervical, colorectal, lung, prostate and thyroid cancer, diagnosed between 2004 and 2017;
• to estimate trends between 2004 and 2017 in cancer incidence rates by stage at diagnosis for breast, cervical, colorectal, lung, prostate and thyroid cancer, in Cyprus;
• to compare breast cancer incidence rates by stage at diagnosis before and after the introduction of mammography as a national screening programme (for the age groups targeted by the screening programme);
• to identify factors (determinants) associated with late stage diagnosis for breast, cervical, colorectal, lung, prostate and thyroid cancer diagnosed between 2004 and 2017, in Cyprus;
• to estimate stage-specific survival rates at one, three and five years after diagnosis for breast, cervical, colorectal, lung, prostate and thyroid cancer diagnosed between 2004 and 2017, in Cyprus; and
• to compare the distribution of stage at diagnosis, trends in cancer incidence rates by stage at diagnosis and stage-specific survival rates for breast, cervical, colorectal, lung, prostate and thyroid cancer, between the Cypriot population and other countries, for the same time period.

The STADICAN project is carried out in collaboration with the Cyprus Cancer Registry (CyCR), Health Monitoring Unit, Ministry of Health, Republic of Cyprus. The CyCR is a population-based cancer registry that was established in 1988. The CyCR collects data on cancer diagnoses from all public and private hospitals as well as from clinics within the Republic of Cyprus, covering the government-controlled southern part of the island of Cyprus.

Key findings

- Rural area residents have higher odds of a late Breast Cancer TSD (regional/distant)
- Rural area BC patients have higher odds of dying
- After the introduction of the screening programme (2007), for the targeted age group, rural place of residence was still associated with higher odds of late TSD but not with higher odds of death


- Over the study period, survival improvements (5-year net survival) were observed for both lung and colorectal cancer.
- Late stage at diagnosis seems to be a contributing factor to decreased survival, as well as to minimal improvements in 5-yesr net survival over the years, of lung or colorectal cancer patients in Cyprus.

AcronymSTADICAN
StatusActive
Effective start/end date1/11/19 → …

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