TY - JOUR
T1 - A case of signet ring carcinoma of the appendix
T2 - Dilemmas in differential diagnosis and management
AU - Mastoraki, Aikaterini
AU - Papanikolaou, Ioannis S.
AU - Kanakis, Dimitrios
AU - Safioleas, Panagiotis
AU - Sakorafas, George
AU - Safioleas, Michael
PY - 2010/6
Y1 - 2010/6
N2 - Purpose Signet ring carcinoma (SRC) of the appendix consists one of the most biologically virulent cancers. We present the case of a patient with primary SRC complicated by the development of acute inflammation of the appendix. Case Report A 78-year-old man was admitted due to a 5-day history of increasing colicky abdominal pain and vomiting. Clinical examination revealed a firm, tender mass in the right ileac fossa. Laparotomy confirmed a tumor mass which appeared to originate from the appendix. The affected part of the bowel was resected and a right hemicolectomy with an end-to-side ileotransverse anastomosis was performed. The appendix was notably thickened with an ulcerated wall containing sinus tracts, chronic inflammation, and scarring. Moreover, a focus of SRC was detected. Conclusions Appendiceal SRC is a rare entity, which may sometimes be confused with other pathologies providing difficulties in differential diagnosis, having an impact on therapeutic decisions and affecting prognosis.
AB - Purpose Signet ring carcinoma (SRC) of the appendix consists one of the most biologically virulent cancers. We present the case of a patient with primary SRC complicated by the development of acute inflammation of the appendix. Case Report A 78-year-old man was admitted due to a 5-day history of increasing colicky abdominal pain and vomiting. Clinical examination revealed a firm, tender mass in the right ileac fossa. Laparotomy confirmed a tumor mass which appeared to originate from the appendix. The affected part of the bowel was resected and a right hemicolectomy with an end-to-side ileotransverse anastomosis was performed. The appendix was notably thickened with an ulcerated wall containing sinus tracts, chronic inflammation, and scarring. Moreover, a focus of SRC was detected. Conclusions Appendiceal SRC is a rare entity, which may sometimes be confused with other pathologies providing difficulties in differential diagnosis, having an impact on therapeutic decisions and affecting prognosis.
KW - Appendix
KW - Literature review
KW - Signet ring carcinoma
KW - Surgical management
UR - http://www.scopus.com/inward/record.url?scp=77954624143&partnerID=8YFLogxK
U2 - 10.1007/s12029-009-9123-6
DO - 10.1007/s12029-009-9123-6
M3 - Article
C2 - 20058100
AN - SCOPUS:77954624143
SN - 1941-6628
VL - 41
SP - 141
EP - 144
JO - Journal of Gastrointestinal Cancer
JF - Journal of Gastrointestinal Cancer
IS - 2
ER -