A correction to the calculation of the Gibbs free energy of adsorption for biomolecules in ion-exchange systems

Costas S. Patrickios, Edna N. Yamasaki

Research output: Contribution to journalArticlepeer-review

8 Citations (Scopus)

Abstract

We wish to propose a correction to the methodology introduced by Gerstner et al. [J.A. Gerstner, J.A. Bell, S.M. Cramer, Biophys. Chem. 52 (1994) 97-106] for the calculation of Gibbs free energies of adsorption of biomolecules to ion-exchange systems, Our approach is based on the requirement that the mobile phase and stationary phase concentrations be expressed in exactly the same units and the equilibrium constant be strictly dimensionless. The Gibbs free energies of ion-exchange calculated based on this correction appear to be more negative than those originally calculated by Gerstner et al.

Original languageEnglish
Pages (from-to)219-220
Number of pages2
JournalBiophysical Chemistry
Volume69
Issue number2-3
DOIs
Publication statusPublished - 1 Dec 1997

Keywords

  • Gibbs free energy of adsorption
  • Ion-exchange systems
  • Mobile phase
  • Stationary phase

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