TY - JOUR
T1 - A correction to the calculation of the Gibbs free energy of adsorption for biomolecules in ion-exchange systems
AU - Patrickios, Costas S.
AU - Yamasaki, Edna N.
PY - 1997/12/1
Y1 - 1997/12/1
N2 - We wish to propose a correction to the methodology introduced by Gerstner et al. [J.A. Gerstner, J.A. Bell, S.M. Cramer, Biophys. Chem. 52 (1994) 97-106] for the calculation of Gibbs free energies of adsorption of biomolecules to ion-exchange systems, Our approach is based on the requirement that the mobile phase and stationary phase concentrations be expressed in exactly the same units and the equilibrium constant be strictly dimensionless. The Gibbs free energies of ion-exchange calculated based on this correction appear to be more negative than those originally calculated by Gerstner et al.
AB - We wish to propose a correction to the methodology introduced by Gerstner et al. [J.A. Gerstner, J.A. Bell, S.M. Cramer, Biophys. Chem. 52 (1994) 97-106] for the calculation of Gibbs free energies of adsorption of biomolecules to ion-exchange systems, Our approach is based on the requirement that the mobile phase and stationary phase concentrations be expressed in exactly the same units and the equilibrium constant be strictly dimensionless. The Gibbs free energies of ion-exchange calculated based on this correction appear to be more negative than those originally calculated by Gerstner et al.
KW - Gibbs free energy of adsorption
KW - Ion-exchange systems
KW - Mobile phase
KW - Stationary phase
UR - http://www.scopus.com/inward/record.url?scp=0031469018&partnerID=8YFLogxK
U2 - 10.1016/S0301-4622(97)00095-1
DO - 10.1016/S0301-4622(97)00095-1
M3 - Article
C2 - 17029929
AN - SCOPUS:0031469018
SN - 0301-4622
VL - 69
SP - 219
EP - 220
JO - Biophysical Chemistry
JF - Biophysical Chemistry
IS - 2-3
ER -