Abstract
A direct correlation of QEMG with muscle biopsy findings might help delineate the sensitivity of QEMG in identifying muscle pathology as well as provide information on electrophysiological-histological correlations. In a study of 31 patients with a variety of myopathies we found that the sensitivity of QEMG was between 24 to 69% depending of the specific method of signal analysis. The positive predictive value of abnormal QEMG was more than 90% while its negative predictive value was only about 20%. Amplitude outlier analysis was superior especially in minimally weak muscles (MRC > 4) and was particularly sensitive at detecting increased variability in fiber size and more subtle myopathic changes.
Original language | English |
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Pages (from-to) | 37-41 |
Number of pages | 5 |
Journal | Acta Myologica |
Volume | 30 |
Issue number | JUNE |
Publication status | Published - Jun 2011 |
Keywords
- Muscle biopsy
- Quantitative electromyography
- Sensitivity