A correlative study of quantitative EMG and biopsy findings in 31 patients with myopathies

E. Dardiotis, E. Papathanasiou, I. Vonta, G. Hadjigeorgiou, E. Zamba-Papanicolaou, Theodoros Kyriakides

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Abstract

A direct correlation of QEMG with muscle biopsy findings might help delineate the sensitivity of QEMG in identifying muscle pathology as well as provide information on electrophysiological-histological correlations. In a study of 31 patients with a variety of myopathies we found that the sensitivity of QEMG was between 24 to 69% depending of the specific method of signal analysis. The positive predictive value of abnormal QEMG was more than 90% while its negative predictive value was only about 20%. Amplitude outlier analysis was superior especially in minimally weak muscles (MRC > 4) and was particularly sensitive at detecting increased variability in fiber size and more subtle myopathic changes.

Original languageEnglish
Pages (from-to)37-41
Number of pages5
JournalActa Myologica
Volume30
Issue numberJUNE
Publication statusPublished - Jun 2011

Keywords

  • Muscle biopsy
  • Quantitative electromyography
  • Sensitivity

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    Dardiotis, E., Papathanasiou, E., Vonta, I., Hadjigeorgiou, G., Zamba-Papanicolaou, E., & Kyriakides, T. (2011). A correlative study of quantitative EMG and biopsy findings in 31 patients with myopathies. Acta Myologica, 30(JUNE), 37-41.