TY - JOUR
T1 - Adaptation and development of software simulation methodologies for cardiovascular engineering
T2 - Present and future challenges from an end-user perspective
AU - Díaz-Zuccarini, V.
AU - Narracott, A. J.
AU - Burriesci, G.
AU - Zervides, C.
AU - Rafiroiu, D.
AU - Jones, D.
AU - Hose, D. R.
AU - Lawford, P. V.
PY - 2009/7/13
Y1 - 2009/7/13
N2 - This paper describes the use of diverse software tools in cardiovascular applications. These tools were primarily developed in the field of engineering and the applications presented push the boundaries of the software to address events related to venous and arterial valve closure, exploration of dynamic boundary conditions or the inclusion of multi-scale boundary conditions from protein to organ levels. The future of cardiovascular research and the challenges that modellers and clinicians face from validation to clinical uptake are discussed from an end-user perspective.
AB - This paper describes the use of diverse software tools in cardiovascular applications. These tools were primarily developed in the field of engineering and the applications presented push the boundaries of the software to address events related to venous and arterial valve closure, exploration of dynamic boundary conditions or the inclusion of multi-scale boundary conditions from protein to organ levels. The future of cardiovascular research and the challenges that modellers and clinicians face from validation to clinical uptake are discussed from an end-user perspective.
KW - Biological modelling
KW - Cardiovascular modelling and simulation
KW - Multi-scale modelling
KW - Patient-specific simulations
KW - Simulation software
KW - Virtual physiological human
UR - http://www.scopus.com/inward/record.url?scp=67650340454&partnerID=8YFLogxK
U2 - 10.1098/rsta.2009.0052
DO - 10.1098/rsta.2009.0052
M3 - Article
C2 - 19487202
AN - SCOPUS:67650340454
SN - 1364-503X
VL - 367
SP - 2655
EP - 2666
JO - Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences
JF - Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences
IS - 1898
ER -