Adaptation and development of software simulation methodologies for cardiovascular engineering: Present and future challenges from an end-user perspective

V. Díaz-Zuccarini, A. J. Narracott, G. Burriesci, C. Zervides, D. Rafiroiu, D. Jones, D. R. Hose, P. V. Lawford

Research output: Contribution to journalArticlepeer-review

Abstract

This paper describes the use of diverse software tools in cardiovascular applications. These tools were primarily developed in the field of engineering and the applications presented push the boundaries of the software to address events related to venous and arterial valve closure, exploration of dynamic boundary conditions or the inclusion of multi-scale boundary conditions from protein to organ levels. The future of cardiovascular research and the challenges that modellers and clinicians face from validation to clinical uptake are discussed from an end-user perspective.

Original languageEnglish
Pages (from-to)2655-2666
Number of pages12
JournalPhilosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences
Volume367
Issue number1898
DOIs
Publication statusPublished - 13 Jul 2009
Externally publishedYes

Keywords

  • Biological modelling
  • Cardiovascular modelling and simulation
  • Multi-scale modelling
  • Patient-specific simulations
  • Simulation software
  • Virtual physiological human

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