Agitation and postdexamethasone cortisol levels in Alzheimer's disease

Brian A. Lawlor; Gabriel Tsuboyama; Theresa Ryan; Richard C. Mohs; Bonnie M. Davis; Michael Davidson; Steven Gabriel; Kenneth L. Davis

Agitation and postdexamethasone cortisol levels in Alzheimer's disease

Brian A. Lawlor
, Gabriel Tsuboyama
, Theresa Ryan
, Richard C. Mohs
, Bonnie M. Davis
, Michael Davidson
, Steven Gabriel
, Kenneth L. Davis

Research output: Contribution to journal › Article › peer-review

Abstract

The clinical correlates of hypothalamic-pituitary-adrenal (HPA) functioning were examined in 29 patients with probable Alzheimer's disease. The 8:00 a.m. postdexamethasone cortisol levels of these patients were highly correlated with higher agitation scores but not with the degree of depressed mood or memory impairment. The possible neural basis for the association between hypercortisolism and behavioral disturbance in Alzheimer's disease warrants further exploration and replication.

Original language	English
Pages (from-to)	546-548
Number of pages	3
Journal	American Journal of Psychiatry
Volume	149
Issue number	4
Publication status	Published - 1992
Externally published	Yes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Cite this

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title = "Agitation and postdexamethasone cortisol levels in Alzheimer's disease",

abstract = "The clinical correlates of hypothalamic-pituitary-adrenal (HPA) functioning were examined in 29 patients with probable Alzheimer's disease. The 8:00 a.m. postdexamethasone cortisol levels of these patients were highly correlated with higher agitation scores but not with the degree of depressed mood or memory impairment. The possible neural basis for the association between hypercortisolism and behavioral disturbance in Alzheimer's disease warrants further exploration and replication.",

author = "Lawlor, \{Brian A.\} and Gabriel Tsuboyama and Theresa Ryan and Mohs, \{Richard C.\} and Davis, \{Bonnie M.\} and Michael Davidson and Steven Gabriel and Davis, \{Kenneth L.\}",

year = "1992",

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journal = "American Journal of Psychiatry",

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AU - Lawlor, Brian A.

AU - Tsuboyama, Gabriel

AU - Ryan, Theresa

AU - Mohs, Richard C.

AU - Davis, Bonnie M.

AU - Davidson, Michael

AU - Gabriel, Steven

AU - Davis, Kenneth L.

PY - 1992

Y1 - 1992

N2 - The clinical correlates of hypothalamic-pituitary-adrenal (HPA) functioning were examined in 29 patients with probable Alzheimer's disease. The 8:00 a.m. postdexamethasone cortisol levels of these patients were highly correlated with higher agitation scores but not with the degree of depressed mood or memory impairment. The possible neural basis for the association between hypercortisolism and behavioral disturbance in Alzheimer's disease warrants further exploration and replication.

AB - The clinical correlates of hypothalamic-pituitary-adrenal (HPA) functioning were examined in 29 patients with probable Alzheimer's disease. The 8:00 a.m. postdexamethasone cortisol levels of these patients were highly correlated with higher agitation scores but not with the degree of depressed mood or memory impairment. The possible neural basis for the association between hypercortisolism and behavioral disturbance in Alzheimer's disease warrants further exploration and replication.

UR - https://www.scopus.com/pages/publications/0026529402

M3 - Article

C2 - 1554044

AN - SCOPUS:0026529402

SN - 0002-953X

VL - 149

SP - 546

EP - 548

JO - American Journal of Psychiatry

JF - American Journal of Psychiatry

IS - 4

ER -

Agitation and postdexamethasone cortisol levels in Alzheimer's disease

Abstract

UN SDGs

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