Alzheimer's-disease-related protein in geriatric schizophrenic patients with cognitive impairment

Peter Powchik; Michael Davidson; Charles B. Nemeroff; Vahram Haroutunian; Dushyant Purohit; Miklos Losonczy; Garth Bissette; Daniel Perl; Hossein Ghanbari; Barney Miller; Kenneth L. Davis

doi:10.1176/ajp.150.11.1726

Alzheimer's-disease-related protein in geriatric schizophrenic patients with cognitive impairment

Peter Powchik
, Michael Davidson
, Charles B. Nemeroff
, Vahram Haroutunian
, Dushyant Purohit
, Miklos Losonczy
, Garth Bissette
, Daniel Perl
, Hossein Ghanbari
, Barney Miller
, Kenneth L. Davis

Research output: Contribution to journal › Article › peer-review

Abstract

The authors compared Alz-50 immunoreactivity in the brain tissue of nine cognitively impaired elderly schizophrenic patients and 13 elderly comparison subjects, both without neuritic plaques or neurofibrillary tangles, and 13 patients with Alzheimer's disease. Alz-50 reactivity was absent in the schizophrenic patients, indicating that geriatric, cognitively impaired patients are unlikely to display the pathology of Alzheimer's disease.

Original language	English
Pages (from-to)	1726-1727
Number of pages	2
Journal	American Journal of Psychiatry
Volume	150
Issue number	11
DOIs	https://doi.org/10.1176/ajp.150.11.1726
Publication status	Published - 1993
Externally published	Yes

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This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

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10.1176/ajp.150.11.1726

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title = "Alzheimer's-disease-related protein in geriatric schizophrenic patients with cognitive impairment",

abstract = "The authors compared Alz-50 immunoreactivity in the brain tissue of nine cognitively impaired elderly schizophrenic patients and 13 elderly comparison subjects, both without neuritic plaques or neurofibrillary tangles, and 13 patients with Alzheimer's disease. Alz-50 reactivity was absent in the schizophrenic patients, indicating that geriatric, cognitively impaired patients are unlikely to display the pathology of Alzheimer's disease.",

author = "Peter Powchik and Michael Davidson and Nemeroff, \{Charles B.\} and Vahram Haroutunian and Dushyant Purohit and Miklos Losonczy and Garth Bissette and Daniel Perl and Hossein Ghanbari and Barney Miller and Davis, \{Kenneth L.\}",

year = "1993",

doi = "10.1176/ajp.150.11.1726",

language = "English",

volume = "150",

pages = "1726--1727",

journal = "American Journal of Psychiatry",

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TY - JOUR

T1 - Alzheimer's-disease-related protein in geriatric schizophrenic patients with cognitive impairment

AU - Powchik, Peter

AU - Davidson, Michael

AU - Nemeroff, Charles B.

AU - Haroutunian, Vahram

AU - Purohit, Dushyant

AU - Losonczy, Miklos

AU - Bissette, Garth

AU - Perl, Daniel

AU - Ghanbari, Hossein

AU - Miller, Barney

AU - Davis, Kenneth L.

PY - 1993

Y1 - 1993

N2 - The authors compared Alz-50 immunoreactivity in the brain tissue of nine cognitively impaired elderly schizophrenic patients and 13 elderly comparison subjects, both without neuritic plaques or neurofibrillary tangles, and 13 patients with Alzheimer's disease. Alz-50 reactivity was absent in the schizophrenic patients, indicating that geriatric, cognitively impaired patients are unlikely to display the pathology of Alzheimer's disease.

AB - The authors compared Alz-50 immunoreactivity in the brain tissue of nine cognitively impaired elderly schizophrenic patients and 13 elderly comparison subjects, both without neuritic plaques or neurofibrillary tangles, and 13 patients with Alzheimer's disease. Alz-50 reactivity was absent in the schizophrenic patients, indicating that geriatric, cognitively impaired patients are unlikely to display the pathology of Alzheimer's disease.

UR - https://www.scopus.com/pages/publications/0027361470

U2 - 10.1176/ajp.150.11.1726

DO - 10.1176/ajp.150.11.1726

M3 - Article

C2 - 8214183

AN - SCOPUS:0027361470

SN - 0002-953X

VL - 150

SP - 1726

EP - 1727

JO - American Journal of Psychiatry

JF - American Journal of Psychiatry

IS - 11

ER -

Alzheimer's-disease-related protein in geriatric schizophrenic patients with cognitive impairment

Abstract

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