Abstract
We present the use of multiscale Amplitude Modulation Frequency Modulation (AM-FM) methods for analyzing brain white matter lesions that are associated with disease progression. We analyze lesions and normal appearing white matter (NAWM) longitudinally (0 and 6 months) and also for progression of disease. We use the expanded disability status scale (EDSS) to assess disease progression. The findings suggest that the high-frequency scale instantaneous amplitude can be used to differentiate between lesions associated with early and advanced disease stages. The classification results using the IF information and support vector machines produced a maximum sensitivity of 0.86, specificity of 0.76 and a maximum correct classification of 0.71.
Original language | English |
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Title of host publication | 2010 IEEE Southwest Symposium on Image Analysis and Interpretation, SSIAI 2010 - Proceedings |
Pages | 61-64 |
Number of pages | 4 |
DOIs | |
Publication status | Published - 2010 |
Event | 2010 IEEE Southwest Symposium on Image Analysis and Interpretation, SSIAI 2010 - Austin, TX, United States Duration: 23 May 2010 → 25 May 2010 |
Other
Other | 2010 IEEE Southwest Symposium on Image Analysis and Interpretation, SSIAI 2010 |
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Country/Territory | United States |
City | Austin, TX |
Period | 23/05/10 → 25/05/10 |
Keywords
- MRI
- Multiple sclerosis
- Multiscale AM-FM analysis