AM-FM texture image analysis in brain white matter lesions in the progression of multiple sclerosis

C. P. Loizou, V. Murray, M. S. Pattichis, M. Pantziaris, C. S. Pattichis

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

1 Citation (Scopus)

Abstract

We present the use of multiscale Amplitude Modulation Frequency Modulation (AM-FM) methods for analyzing brain white matter lesions that are associated with disease progression. We analyze lesions and normal appearing white matter (NAWM) longitudinally (0 and 6 months) and also for progression of disease. We use the expanded disability status scale (EDSS) to assess disease progression. The findings suggest that the high-frequency scale instantaneous amplitude can be used to differentiate between lesions associated with early and advanced disease stages. The classification results using the IF information and support vector machines produced a maximum sensitivity of 0.86, specificity of 0.76 and a maximum correct classification of 0.71.

Original languageEnglish
Title of host publication2010 IEEE Southwest Symposium on Image Analysis and Interpretation, SSIAI 2010 - Proceedings
Pages61-64
Number of pages4
DOIs
Publication statusPublished - 2010
Event2010 IEEE Southwest Symposium on Image Analysis and Interpretation, SSIAI 2010 - Austin, TX, United States
Duration: 23 May 201025 May 2010

Other

Other2010 IEEE Southwest Symposium on Image Analysis and Interpretation, SSIAI 2010
Country/TerritoryUnited States
CityAustin, TX
Period23/05/1025/05/10

Keywords

  • MRI
  • Multiple sclerosis
  • Multiscale AM-FM analysis

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