An overview of recent treatment options for primary sclerosing cholangitis

Ioanna Mousavere, Georgios Kalampokis, Fotios Fousekis, Peter Karayiannis, Gerasimos Baltayiannis, Dimitrios Christodoulou

    Research output: Contribution to journalReview articlepeer-review


    Primary sclerosing cholangitis (PSC) is a chronic hepatic dysfunction characterized by inflammatory and tissue-degenerative strictures of the biliary tree, leading to cirrhosis and cholangiocarcinoma. The pathophysiological mechanisms involve immune-mediated responses. Numerous treatment modalities targeting the inflammatory aspects have been suggested, but a consensus on the best treatment option is lacking. This study aims to review the most up-to-date treatment options for PSC.

    Original languageEnglish
    Pages (from-to)589
    Number of pages1
    JournalAnnals of Gastroenterology
    Issue number6
    Publication statusPublished - 23 Nov 2023


    • management
    • Primary sclerosing cholangitis
    • treatment


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