An overview of recent treatment options for primary sclerosing cholangitis

Ioanna Mousavere; Georgios Kalampokis; Fotios Fousekis; Peter Karayiannis; Gerasimos Baltayiannis; Dimitrios Christodoulou

doi:10.20524/aog.2023.0834

An overview of recent treatment options for primary sclerosing cholangitis

Ioanna Mousavere, Georgios Kalampokis, Fotios Fousekis, Peter Karayiannis, Gerasimos Baltayiannis, Dimitrios Christodoulou

Research output: Contribution to journal › Review article › peer-review

Abstract

Primary sclerosing cholangitis (PSC) is a chronic hepatic dysfunction characterized by inflammatory and tissue-degenerative strictures of the biliary tree, leading to cirrhosis and cholangiocarcinoma. The pathophysiological mechanisms involve immune-mediated responses. Numerous treatment modalities targeting the inflammatory aspects have been suggested, but a consensus on the best treatment option is lacking. This study aims to review the most up-to-date treatment options for PSC.

Original language	English
Pages (from-to)	589
Number of pages	1
Journal	Annals of Gastroenterology
Volume	36
Issue number	6
DOIs	https://doi.org/10.20524/aog.2023.0834
Publication status	Published - 23 Nov 2023

Keywords

management
Primary sclerosing cholangitis
treatment

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10.20524/aog.2023.0834

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title = "An overview of recent treatment options for primary sclerosing cholangitis",

abstract = "Primary sclerosing cholangitis (PSC) is a chronic hepatic dysfunction characterized by inflammatory and tissue-degenerative strictures of the biliary tree, leading to cirrhosis and cholangiocarcinoma. The pathophysiological mechanisms involve immune-mediated responses. Numerous treatment modalities targeting the inflammatory aspects have been suggested, but a consensus on the best treatment option is lacking. This study aims to review the most up-to-date treatment options for PSC.",

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AU - Mousavere, Ioanna

AU - Kalampokis, Georgios

AU - Fousekis, Fotios

AU - Karayiannis, Peter

AU - Baltayiannis, Gerasimos

AU - Christodoulou, Dimitrios

PY - 2023/11/23

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N2 - Primary sclerosing cholangitis (PSC) is a chronic hepatic dysfunction characterized by inflammatory and tissue-degenerative strictures of the biliary tree, leading to cirrhosis and cholangiocarcinoma. The pathophysiological mechanisms involve immune-mediated responses. Numerous treatment modalities targeting the inflammatory aspects have been suggested, but a consensus on the best treatment option is lacking. This study aims to review the most up-to-date treatment options for PSC.

AB - Primary sclerosing cholangitis (PSC) is a chronic hepatic dysfunction characterized by inflammatory and tissue-degenerative strictures of the biliary tree, leading to cirrhosis and cholangiocarcinoma. The pathophysiological mechanisms involve immune-mediated responses. Numerous treatment modalities targeting the inflammatory aspects have been suggested, but a consensus on the best treatment option is lacking. This study aims to review the most up-to-date treatment options for PSC.

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M3 - Review article

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ER -

An overview of recent treatment options for primary sclerosing cholangitis

Abstract

Keywords

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