Benign and malignant pathology of the uterus

V. Tanos, K. E. Berry

Research output: Contribution to journalReview articlepeer-review

11 Citations (Scopus)


The diagnosis of a uterine myoma size and location can be very precise when a 3D sonograph and knowledge are available. The majority of fibroids are asymptomatic, and expectant management is recommended. In young patients, fibroids cause infertility and in middle-aged women, abnormal uterine bleedings. Laparoscopic myomectomy is the preferred way of surgery for IM and SS fibroids, versus hysteroscopy for SM fibroids. In both cases, the size, number of fibroids and the surgeon's experience determine the limitations of the MIGS. Medical treatments provide only temporary tumor reduction and symptom alleviation. Leiomyosarcoma risk is higher in older women usually carrying fibroids larger than 8 cm. There are no other pathognomonic parameters ruling out a sarcoma. In case of suspected fibroid malignancy, the best treatment option is laparotomy and total hysterectomy. Myomectomy complications can be reduced when MIGS is performed by a surgeon with proper training and experience.

Original languageEnglish
Pages (from-to)12-30
Number of pages19
JournalBest Practice and Research: Clinical Obstetrics and Gynaecology
Publication statusPublished - 1 Jan 2018


  • Hysteroscopic myomectomy
  • Imaging
  • Laparoscopic myomectomy
  • Myoma and infertility
  • Uterine fibroid
  • Uterine sarcoma


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