TY - JOUR
T1 - Breakthrough SARS-CoV-2 infections after vaccination
T2 - a critical review
AU - Mohseni Afshar, Zeinab
AU - Barary, Mohammad
AU - Hosseinzadeh, Rezvan
AU - Alijanpour, Amirmasoud
AU - Hosseinzadeh, Dariush
AU - Ebrahimpour, Soheil
AU - Nazary, Kosar
AU - Sio, Terence T.
AU - Sullman, Mark J.M.
AU - Carson-Chahhoud, Kristin
AU - Babazadeh, Arefeh
N1 - Publisher Copyright:
© 2022 The Author(s). Published with license by Taylor & Francis Group, LLC.
PY - 2022
Y1 - 2022
N2 - At the beginning of the current pandemic, it was believed that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection would induce lifelong immunity and that reinfections would be unlikely. However, after several cases of reinfection were documented in previously infected patients, this was understood to be a false assumption, and this waning humoral immunity has raised significant concerns. Accordingly, long-term and durable vaccine-induced antibody protection against infection have also become a challenge, as several breakthroughs of COVID-19 infection have been identified in individuals who were fully vaccinated. This review discusses the current evidence on breakthrough COVID-19 infections occurring after vaccination.
AB - At the beginning of the current pandemic, it was believed that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection would induce lifelong immunity and that reinfections would be unlikely. However, after several cases of reinfection were documented in previously infected patients, this was understood to be a false assumption, and this waning humoral immunity has raised significant concerns. Accordingly, long-term and durable vaccine-induced antibody protection against infection have also become a challenge, as several breakthroughs of COVID-19 infection have been identified in individuals who were fully vaccinated. This review discusses the current evidence on breakthrough COVID-19 infections occurring after vaccination.
KW - breakthrough
KW - COVID-19
KW - immunization
KW - SARS-CoV-2
KW - vaccination
UR - https://www.scopus.com/pages/publications/85126785867
U2 - 10.1080/21645515.2022.2051412
DO - 10.1080/21645515.2022.2051412
M3 - Review article
C2 - 35302905
AN - SCOPUS:85126785867
SN - 2164-5515
VL - 18
JO - Human Vaccines and Immunotherapeutics
JF - Human Vaccines and Immunotherapeutics
IS - 5
M1 - 2051412
ER -
