Comparison of cefonicid and cefazolin prophylaxis in abdominal hysterectomy

Vasilios Tanos, Nathan Rojansky, Shaoul O. Anteby

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)


One hundred and sixty-four patients undergoing abdominal hysterectomy for benign diseaseswere prospectively evaluated. The efficacy and safety of surgical prophylaxis with a single dose of the long-acting cefonicid was compared to the standard three dose regimen of cefazolin. Prophylaxis was successful in 82 of 85 (96.5%) patients receiving cefonicid and in 77 of 79 (97.5%) patients receiving cefazolin. No serious adverse effects were encountered with both drugs. It is concluded that single dose intravenous cefonicid, when given pre- operatively, is as safe and effective as the standard multiple dose regimen of cefazolin in patients undergoing elective abdominal hysterectomy.

Original languageEnglish
Pages (from-to)115-117
Number of pages3
JournalGynecologic and Obstetric Investigation
Issue number2
Publication statusPublished - 1994


  • Abdominal hysterectomy
  • Cefazolin
  • Cefonicid
  • Surgical prophylaxis


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