Abstract
One hundred and sixty-four patients undergoing abdominal hysterectomy for benign diseaseswere prospectively evaluated. The efficacy and safety of surgical prophylaxis with a single dose of the long-acting cefonicid was compared to the standard three dose regimen of cefazolin. Prophylaxis was successful in 82 of 85 (96.5%) patients receiving cefonicid and in 77 of 79 (97.5%) patients receiving cefazolin. No serious adverse effects were encountered with both drugs. It is concluded that single dose intravenous cefonicid, when given pre- operatively, is as safe and effective as the standard multiple dose regimen of cefazolin in patients undergoing elective abdominal hysterectomy.
| Original language | English |
|---|---|
| Pages (from-to) | 115-117 |
| Number of pages | 3 |
| Journal | Gynecologic and Obstetric Investigation |
| Volume | 37 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - 1994 |
Keywords
- Abdominal hysterectomy
- Cefazolin
- Cefonicid
- Surgical prophylaxis