TY - JOUR
T1 - Cutoff points of waist circumference and trunk and visceral fat for identifying children with elevated inflammation markers and adipokines
T2 - The Healthy Growth Study
AU - Healthy Growth Study group
AU - Karatzi, Kalliopi
AU - Moschonis, George
AU - Polychronopoulou, Maria Christina
AU - Chrousos, George P.
AU - Lionis, Christos
AU - Manios, Yannis
AU - Manios, Yannis
AU - Skenderi, Katerina P.
AU - Grammatikaki, Evangelia
AU - Androutsos, Odysseas
AU - Tanagra, Sofia
AU - Koumpitski, Alexandra
AU - Siatitsa, Paraskevi Eirini
AU - Vandorou, Anastasia
AU - Kyriakou, Aikaterini Efstathia
AU - Dede, Vasiliki
AU - Kantilafti, Maria
AU - Farmaki, Aliki Eleni
AU - Siopi, Aikaterini
AU - Micheli, Sofia
AU - Damianidi, Louiza
AU - Margiola, Panagiota
AU - Gakni, Despoina
AU - Iatridi, Vasiliki
AU - Mavrogianni, Christina
AU - Michailidou, Kelaidi
AU - Giannopoulou, Aggeliki
AU - Argyri, Efstathoula
AU - Maragkopoulou, Konstantina
AU - Spyridonos, Maria
AU - Tsikalaki, Eirini
AU - Kliasios, Panagiotis
AU - Naoumi, Anthi
AU - Koutsikas, Konstantinos
AU - Aggelou, Epistimi
AU - Krommyda, Zoi
AU - Aga, Charitini
AU - Birbilis, Manolis
AU - Kosteria, Ioanna
AU - Zlatintsi, Amalia
AU - Voutsadaki, Elpida
AU - Papadopoulou, Eleni Zouboulia
AU - Papazi, Zoi
AU - Papadogiorgakaki, Maria
AU - Chlouveraki, Fanouria
AU - Lyberi, Maria
AU - Karatsikaki-Vlami, Nora
AU - Dionysopoulou, Eva
AU - Daskalou, Efstratia
PY - 2016/10/1
Y1 - 2016/10/1
N2 - Objectives Excessive fat storage is accompanied by several comorbidities in children and early identification of elevated abdominal fat may be extremely valuable in early prevention of cardiometabolic risk. The aim of the present study was to establish cutoff points for waist circumference trunk and visceral fat, thus identifying increased likelihood of elevated inflammatory markers and adipokines in children. Methods A representative sample of schoolchildren (aged 9–13 y) participated in a cross-sectional epidemiologic study conducted in Greece. Anthropometric and physical examination data, biochemical indices, and socioeconomic information (collected from parents) were assessed for all children. Central adiposity markers (trunk and visceral fat) were collected with bioelectrical impedance analysis for 999 children. Results Specific cutoff values of abdominal adiposity indices indicating increased likelihood of elevated levels of C-reactive protein, interleukin-6, and leptin and decreased levels of adiponectin were calculated by sex. These cutoff values were; 67.5 cm for boys and 69.5 cm for girls for waist circumference, 17.75% for boys and 22.65% for girls for trunk fat mass percentage, and 3.95 for boys and 2.55 for girls for visceral fat rating. Conclusions To our knowledge, this is the first study to establish simple cutoff points for abdominal adiposity indices identifying children at high risk for elevated inflammatory markers and decreased adipokine levels. Future studies are essential to confirm these findings.
AB - Objectives Excessive fat storage is accompanied by several comorbidities in children and early identification of elevated abdominal fat may be extremely valuable in early prevention of cardiometabolic risk. The aim of the present study was to establish cutoff points for waist circumference trunk and visceral fat, thus identifying increased likelihood of elevated inflammatory markers and adipokines in children. Methods A representative sample of schoolchildren (aged 9–13 y) participated in a cross-sectional epidemiologic study conducted in Greece. Anthropometric and physical examination data, biochemical indices, and socioeconomic information (collected from parents) were assessed for all children. Central adiposity markers (trunk and visceral fat) were collected with bioelectrical impedance analysis for 999 children. Results Specific cutoff values of abdominal adiposity indices indicating increased likelihood of elevated levels of C-reactive protein, interleukin-6, and leptin and decreased levels of adiponectin were calculated by sex. These cutoff values were; 67.5 cm for boys and 69.5 cm for girls for waist circumference, 17.75% for boys and 22.65% for girls for trunk fat mass percentage, and 3.95 for boys and 2.55 for girls for visceral fat rating. Conclusions To our knowledge, this is the first study to establish simple cutoff points for abdominal adiposity indices identifying children at high risk for elevated inflammatory markers and decreased adipokine levels. Future studies are essential to confirm these findings.
KW - Adipokines
KW - Cutoff points
KW - Inflammation
KW - Trunk fat
KW - Visceral fat
KW - Waist circumference
UR - http://www.scopus.com/inward/record.url?scp=84964807468&partnerID=8YFLogxK
U2 - 10.1016/j.nut.2016.02.022
DO - 10.1016/j.nut.2016.02.022
M3 - Article
C2 - 27155952
AN - SCOPUS:84964807468
SN - 0899-9007
VL - 32
SP - 1063
EP - 1067
JO - Nutrition
JF - Nutrition
IS - 10
ER -