Description of the first two seemingly unrelated Greek Cypriot families with a common C618R RET proto-oncogene mutation

Keyphrases

• Greek Cypriots 100%
• RET Proto-oncogene 100%
• Multiple Endocrine Neoplasia Type 2 (MEN2) 100%
• Familial Medullary Thyroid Carcinoma 75%
• Direct Sequencing 50%
• Proband 50%
• Exon 10 50%
• ARMS-PCR 50%
• Cyprus 25%
• Codon 25%
• Molecular Characterization 25%
• Clinical Diagnosis 25%
• Clinical Presentation 25%
• Missense mutation 25%
• Genomic DNA (gDNA) 25%
• Germline mutation 25%
• Germ Cells 25%
• RET Gene 25%
• Genetic Diagnosis 25%
• Tumor Marker 25%
• Carcinoembryonic Antigen 25%
• Calcitonin 25%
• Cancer Syndromes 25%
• Clinical Characterization 25%

Biochemistry, Genetics and Molecular Biology

• RET Proto-Oncogene 100%
• Proband 66%
• Exon 66%
• Genetics 33%
• Codon 33%
• Missense Mutation 33%
• DNA Sequence 33%
• Germ Cell 33%
• Germline Mutation 33%
• Tumor Marker 33%
• DNA Template 33%
• Carcinoembryonic Antigen 33%
• Genomics 33%
• Calcitonin 33%