TY - JOUR
T1 - Diastolic Doppler flow and tissue Doppler velocities during, and in recovery from, low-intensity supine exercise
AU - Giannaki, Christoforos D.
AU - Oxborough, David
AU - George, Keith
PY - 2008/10
Y1 - 2008/10
N2 - Recent studies have reported evidence of both a short-term and a more sustained reduction in left ventricular diastolic function after prolonged strenuous exercise. Interpretation of this data is confounded by alterations in heart rate (HR) post-exercise. The purpose of this study was to investigate the association between HR and diastolic function during recovery from supine exercise, and to reassess the impact of increasing HR on early diastolic flow and tissue velocities during supine exercise. Repeat echocardiograms in 16 young, trained, volunteers were obtained at rest (50 ± 6 beats·min-1), during steady-state supine cycling at HR of 60, 80, and 100 beats·min-1, and then during supine recovery at HR of 80 and 60 beats·min-1. Doppler flow velocities and tissue Doppler myocardial annular velocities were recorded in early (E and E′, respectively) and late diastole (A and A′, respectively). The ratios E/A, E′/A′, and E/E′ were calculated. Data were compared via analyses of variance (ANOVA; exercise) and t tests (recovery). Peak E, A, E′, and A′ all increased in line with HR during exercise (p < 0.05) although relatively greater changes in A and A′ resulted in a significant decline in E/A and E′/A′ with increasing HR (p < 0.05). During recovery E, A, E′, and A′ all declined from peak values during exercise (p < 0.05). At 80 beats·min-1, flow and tissue Doppler data were still elevated above resting values and only A was significantly reduced compared with assessments made at the same HR during exercise. Diastolic flow and tissue velocities tended to increase (during supine exercise) and return to baseline (during recovery from exercise) in line with changes in HR. The interpretation of diastolic functional indices measured after physical exertion should be made in light of the present data.
AB - Recent studies have reported evidence of both a short-term and a more sustained reduction in left ventricular diastolic function after prolonged strenuous exercise. Interpretation of this data is confounded by alterations in heart rate (HR) post-exercise. The purpose of this study was to investigate the association between HR and diastolic function during recovery from supine exercise, and to reassess the impact of increasing HR on early diastolic flow and tissue velocities during supine exercise. Repeat echocardiograms in 16 young, trained, volunteers were obtained at rest (50 ± 6 beats·min-1), during steady-state supine cycling at HR of 60, 80, and 100 beats·min-1, and then during supine recovery at HR of 80 and 60 beats·min-1. Doppler flow velocities and tissue Doppler myocardial annular velocities were recorded in early (E and E′, respectively) and late diastole (A and A′, respectively). The ratios E/A, E′/A′, and E/E′ were calculated. Data were compared via analyses of variance (ANOVA; exercise) and t tests (recovery). Peak E, A, E′, and A′ all increased in line with HR during exercise (p < 0.05) although relatively greater changes in A and A′ resulted in a significant decline in E/A and E′/A′ with increasing HR (p < 0.05). During recovery E, A, E′, and A′ all declined from peak values during exercise (p < 0.05). At 80 beats·min-1, flow and tissue Doppler data were still elevated above resting values and only A was significantly reduced compared with assessments made at the same HR during exercise. Diastolic flow and tissue velocities tended to increase (during supine exercise) and return to baseline (during recovery from exercise) in line with changes in HR. The interpretation of diastolic functional indices measured after physical exertion should be made in light of the present data.
KW - Diastolic function
KW - Echocardiography
KW - Heart rate
KW - Preload
UR - http://www.scopus.com/inward/record.url?scp=53649096665&partnerID=8YFLogxK
U2 - 10.1139/H08-078
DO - 10.1139/H08-078
M3 - Article
C2 - 18923564
AN - SCOPUS:53649096665
VL - 33
SP - 896
EP - 902
JO - Applied Physiology, Nutrition and Metabolism
JF - Applied Physiology, Nutrition and Metabolism
SN - 1715-5312
IS - 5
ER -