Effect of sevoflurane on cardiovascular activity at maintenance and emergence from anesthesia during surgery

Yousef Kordi, Nicoletta Nicolaou

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

The purpose of this preliminary study was to investigate the effect of sevoflurane, an inhalational anesthetic agent routinely used during surgery, on patients' cardiovascular activity (Heart Rate - HR, and Perfusion Index - PI) during the maintenance and emergence phases of surgery, as well as identify if there is any significant correlation between HR and PI at either of the two phases of surgery. For the purposes of the study, a publicly available dataset containing patient monitoring data and vital signs recorded during surgery under general anesthesia by the University of Queensland was used. Heart rate (HR) and Perfusion index (PI) were extracted from 11 cases during maintenance and emergence from sevoflurane, and compared using descriptive statistics. Changes in HR between the two states were not significant, but a statistically significant reduction in PI during emergence compared to maintenance was observed. HR and PI were not significantly correlated during either of the surgical phases studied. This preliminary investigation supports further investigation into the use of continuous monitoring of PI values during surgery to reflect the level of the sympathetic nervous system activity and potentially assess the adequacy of anesthesia.

Original languageEnglish
Title of host publication2022 IEEE Workshop on Complexity in Engineering, COMPENG 2022
PublisherInstitute of Electrical and Electronics Engineers Inc.
ISBN (Electronic)9781728171241
DOIs
Publication statusPublished - 2022
Externally publishedYes
Event2022 IEEE Workshop on Complexity in Engineering, COMPENG 2022 - Florence, Italy
Duration: 18 Jul 202220 Jul 2022

Publication series

Name2022 IEEE Workshop on Complexity in Engineering, COMPENG 2022

Conference

Conference2022 IEEE Workshop on Complexity in Engineering, COMPENG 2022
Country/TerritoryItaly
CityFlorence
Period18/07/2220/07/22

Keywords

  • anesthesia
  • heart rate
  • perfusion index
  • sevoflurane

Fingerprint

Dive into the research topics of 'Effect of sevoflurane on cardiovascular activity at maintenance and emergence from anesthesia during surgery'. Together they form a unique fingerprint.

Cite this