Effects of low vitamin D status in rickets and type 1 diabetes in children

D. Papandreou, Z. Karabouta, I. Rousso

Research output: Contribution to journalReview articlepeer-review

1 Citation (Scopus)


Purpose – This paper aims to review the metabolism, epidemiology and treatment of vitamin D and calcium insufficiency as well as its relation to rickets and diabetes type 1 during childhood and adolescence. Design/methodology/approach – The most uptodate and pertinent studies within the literature are included in this narrative review. Findings – Vitamin D deficiency is common in developing countries and exists in both childhood and adult life. The great importance of vitamin D is the moderation of calcium (Ca) and phosphorus (P) homeostasis as well as the absorption of Ca. While insufficiency of vitamin D is a significant contributing factor to the risk of rickets in childhood, it is possible that a more marginal deficiency of vitamin D during life span contributes to osteoporosis as well as potentially to the development of various other chronic diseases such as diabetes type 1. Originality/value – This paper gives a concise, uptodate overview to nutritionists and dietitians on how vitamin D deficiency may effect rickets and type 1 diabetes.

Original languageEnglish
Pages (from-to)447-455
Number of pages9
JournalNutrition & Food Science
Issue number5
Publication statusPublished - 14 Sep 2010


  • Children (age groups)
  • Diabetes
  • Personal health
  • Vitamins


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