Epileptic seizure onset correlates with long term EEG functional brain network properties

Maria Anastasiadou, Avgis Hadjipapas, Manolis Christodoulakis, Eleftherios S. Papathanasiou, Savvas S. Papacostas, Georgios D. Mitsis

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Abstract

We investigated the correlation of epileptic seizure onset times with long term EEG functional brain network properties. To do so, we constructed binary functional brain networks from long-term, multichannel electroencephalographic data recorded from nine patients with epilepsy. The corresponding network properties were quantified using the average network degree. It was found that the network degree (as well as other network properties such as the network efficiency and clustering coefficient) exhibited large fluctuations over time; however, it also exhibited specific periodic temporal structure over different time scales (1.5hr-24hr periods) that was consistent across subjects. We investigated the correlation of the phases of these network periodicities with the seizure onset by using circular statistics. The results showed that the instantaneous phases of the 3.5hr, 5.5hr, 12hr and 24hr network degree periodic components are not uniformly distributed, suggesting that functional network properties are related to seizure generation and occurrence.

Original languageEnglish
Title of host publication2016 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2016
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages2822-2825
Number of pages4
Volume2016-October
ISBN (Electronic)9781457702204
DOIs
Publication statusPublished - 13 Oct 2016
Event38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2016 - Orlando, United States
Duration: 16 Aug 201620 Aug 2016

Other

Other38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2016
CountryUnited States
CityOrlando
Period16/08/1620/08/16

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  • Cite this

    Anastasiadou, M., Hadjipapas, A., Christodoulakis, M., Papathanasiou, E. S., Papacostas, S. S., & Mitsis, G. D. (2016). Epileptic seizure onset correlates with long term EEG functional brain network properties. In 2016 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2016 (Vol. 2016-October, pp. 2822-2825). [7591317] Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/EMBC.2016.7591317