Evaluation of auditory system in preschool children whose mothers had mid-second trimester amniocentesis

Venkat Annapoorna, Yap Seng Chong, Mui Huey Helen Tong, Chinneiya Anandakumar, Kian Hian Yeoh, Sabaratnam Arulkumaran, S. Shanmmuga Ratnam

Research output: Contribution to journalArticle

Abstract

A prospective study was conducted in the Otorhinolaryngology department, National University Hospital, Singapore to evaluate the effects of mid-trimester amniocentesis on the auditory system in preschool children of about four years of age. Fifty-nine children whose mothers had mid-second trimester amniocentesis and 63 children (control group) whose mothers did not have amniocentesis in that pregnancy were recruited. The children were subjected to audiological tests to assess hearing impedance abnormalities. The incidence of prematurity, neonatal admissions, ear and respiratory infections, auditory function, speech and language development in children were evaluated because these factors have a bearing on the development of auditory impedance abnormalities. There was no significant increase in the neonatal admission rates, impairment of speech and language development and auditory function in children whose mothers had mid-second trimester amniocentesis compared with the control group whose mothers did not have amniocentesis. An incidental finding in this study was an increased incidence of respiratory illnesses in the children in the amniocentesis group (57.6%) compared with the control group (30.1%). This needs further evaluation with a properly designed study.

Original languageEnglish
Pages (from-to)207-212
Number of pages6
JournalJournal of Perinatal Medicine
Volume24
Issue number3
Publication statusPublished - 1996

Keywords

  • Auditory system
  • Evaluation
  • Mid-second trimester amniocentesis
  • Preschool children

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    Annapoorna, V., Chong, Y. S., Tong, M. H. H., Anandakumar, C., Yeoh, K. H., Arulkumaran, S., & Shanmmuga Ratnam, S. (1996). Evaluation of auditory system in preschool children whose mothers had mid-second trimester amniocentesis. Journal of Perinatal Medicine, 24(3), 207-212.