TY - JOUR
T1 - Evaluation of auditory system in preschool children whose mothers had mid-second trimester amniocentesis
AU - Annapoorna, Venkat
AU - Chong, Yap Seng
AU - Tong, Mui Huey Helen
AU - Anandakumar, Chinneiya
AU - Yeoh, Kian Hian
AU - Arulkumaran, Sabaratnam
AU - Shanmmuga Ratnam, S.
PY - 1996
Y1 - 1996
N2 - A prospective study was conducted in the Otorhinolaryngology department, National University Hospital, Singapore to evaluate the effects of mid-trimester amniocentesis on the auditory system in preschool children of about four years of age. Fifty-nine children whose mothers had mid-second trimester amniocentesis and 63 children (control group) whose mothers did not have amniocentesis in that pregnancy were recruited. The children were subjected to audiological tests to assess hearing impedance abnormalities. The incidence of prematurity, neonatal admissions, ear and respiratory infections, auditory function, speech and language development in children were evaluated because these factors have a bearing on the development of auditory impedance abnormalities. There was no significant increase in the neonatal admission rates, impairment of speech and language development and auditory function in children whose mothers had mid-second trimester amniocentesis compared with the control group whose mothers did not have amniocentesis. An incidental finding in this study was an increased incidence of respiratory illnesses in the children in the amniocentesis group (57.6%) compared with the control group (30.1%). This needs further evaluation with a properly designed study.
AB - A prospective study was conducted in the Otorhinolaryngology department, National University Hospital, Singapore to evaluate the effects of mid-trimester amniocentesis on the auditory system in preschool children of about four years of age. Fifty-nine children whose mothers had mid-second trimester amniocentesis and 63 children (control group) whose mothers did not have amniocentesis in that pregnancy were recruited. The children were subjected to audiological tests to assess hearing impedance abnormalities. The incidence of prematurity, neonatal admissions, ear and respiratory infections, auditory function, speech and language development in children were evaluated because these factors have a bearing on the development of auditory impedance abnormalities. There was no significant increase in the neonatal admission rates, impairment of speech and language development and auditory function in children whose mothers had mid-second trimester amniocentesis compared with the control group whose mothers did not have amniocentesis. An incidental finding in this study was an increased incidence of respiratory illnesses in the children in the amniocentesis group (57.6%) compared with the control group (30.1%). This needs further evaluation with a properly designed study.
KW - Auditory system
KW - Evaluation
KW - Mid-second trimester amniocentesis
KW - Preschool children
UR - http://www.scopus.com/inward/record.url?scp=0029978914&partnerID=8YFLogxK
M3 - Article
C2 - 8827568
AN - SCOPUS:0029978914
SN - 0300-5577
VL - 24
SP - 207
EP - 212
JO - Journal of Perinatal Medicine
JF - Journal of Perinatal Medicine
IS - 3
ER -