TY - JOUR
T1 - Extensive testing and public health interventions for the control of covid-19 in the republic of cyprus between march and may 2020
AU - Quattrocchi, Annalisa
AU - Mamais, Ioannis
AU - Tsioutis, Constantinos
AU - Christaki, Eirini
AU - Constantinou, Costas
AU - Koliou, Maria
AU - Pana, Zoi Dorothea
AU - Silvestros, Valentinos
AU - Theophanous, Fani
AU - Haralambous, Christos
AU - Stylianou, Androulla
AU - Sotiriou, Sotiroula
AU - Athanasiadou, Maria
AU - Kyprianou, Theopisti
AU - Demetriou, Anna
AU - Demetriou, Christiana A.
AU - Kolokotroni, Ourania
AU - Gregoriou, Ioanna
AU - Paphitou, Niki
AU - Panos, George
AU - Kostrikis, Leontios
AU - Karayiannis, Peter
AU - Petrikkos, Georgios
AU - Agathangelou, Petros
AU - Mixides, George
AU - Siakallis, Georgios
AU - Hadjihannas, Linos
AU - Palazis, Lakis
AU - Vavlitou, Anna
AU - Matsentidou-Timiliotou, Chrystalla
AU - Koukios, Dimitris
AU - Adamidi, Tonia
AU - Frangopoulos, Frangiskos
AU - Constantinou, Elizabeth
AU - Nikolopoulos, Georgios
N1 - Publisher Copyright:
© 2020, MDPI AG. All rights reserved.
PY - 2020/11
Y1 - 2020/11
N2 - Coronavirus disease 2019 (COVID-19) has significantly affected the well-being of individuals worldwide. We herein describe the epidemiology of COVID-19 in the Republic of Cyprus during the first epidemic wave (9 March–3 May 2020). We analyzed surveillance data from laboratory-confirmed cases, including targeted testing and population screening. Statistical analyses included logistic regression. During the surveillance period, 64,136 tests (7322.3 per 100,000) were performed, 873 COVID-19 cases were diagnosed, and 20 deaths were reported (2.3%). Health-care workers (HCWs) represented 21.4% of cases. Overall, 19.1% of cases received hospital care and 3.7% required admission to Intensive Care Units. Male sex (adjusted Odds Ratio (aOR): 3.04; 95% Confidence Interval (CI): 1.97–4.69), increasing age (aOR: 1.56; 95%CI: 1.36–1.79), symptoms at diagnosis (aOR: 6.05; 95%CI: 3.18–11.50), and underlying health conditions (aOR: 2.08; 95%CI: 1.31–3.31) were associated with hospitalization. For recovered cases, the median time from first to last second negative test was 21 days. Overall, 119 primary cases reported 616 close contacts, yielding a pooled secondary attack rate of 12% (95%CI: 9.6–14.8%). Three population-based screening projects, and two projects targeting employees and HCWs, involving 25,496 people, revealed 60 positive individuals (0.2%). Early implementation of interventions with targeted and expanded testing facilitated prompt outbreak control on the island.
AB - Coronavirus disease 2019 (COVID-19) has significantly affected the well-being of individuals worldwide. We herein describe the epidemiology of COVID-19 in the Republic of Cyprus during the first epidemic wave (9 March–3 May 2020). We analyzed surveillance data from laboratory-confirmed cases, including targeted testing and population screening. Statistical analyses included logistic regression. During the surveillance period, 64,136 tests (7322.3 per 100,000) were performed, 873 COVID-19 cases were diagnosed, and 20 deaths were reported (2.3%). Health-care workers (HCWs) represented 21.4% of cases. Overall, 19.1% of cases received hospital care and 3.7% required admission to Intensive Care Units. Male sex (adjusted Odds Ratio (aOR): 3.04; 95% Confidence Interval (CI): 1.97–4.69), increasing age (aOR: 1.56; 95%CI: 1.36–1.79), symptoms at diagnosis (aOR: 6.05; 95%CI: 3.18–11.50), and underlying health conditions (aOR: 2.08; 95%CI: 1.31–3.31) were associated with hospitalization. For recovered cases, the median time from first to last second negative test was 21 days. Overall, 119 primary cases reported 616 close contacts, yielding a pooled secondary attack rate of 12% (95%CI: 9.6–14.8%). Three population-based screening projects, and two projects targeting employees and HCWs, involving 25,496 people, revealed 60 positive individuals (0.2%). Early implementation of interventions with targeted and expanded testing facilitated prompt outbreak control on the island.
KW - Contact tracing
KW - Containment measures
KW - COVID-19
KW - Cyprus
KW - Pandemic
KW - Surveillance
UR - http://www.scopus.com/inward/record.url?scp=85104807104&partnerID=8YFLogxK
U2 - 10.3390/jcm9113598
DO - 10.3390/jcm9113598
M3 - Article
AN - SCOPUS:85104807104
SN - 2077-0383
VL - 9
SP - 1
EP - 13
JO - Journal of Clinical Medicine
JF - Journal of Clinical Medicine
IS - 11
M1 - 3598
ER -