Failure to detect nucleic acid homology between some non‐A, Non‐B viruses and hepatitis B virus DNA

M. J.F. Fowler, J. Monjardino, I. V. Weller, M. Bamber, P. Karayiannis, A. J. Zuckerman, H. C. Thomas

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Some studies suggest that there is antigenic and nucleic acid homology of one type of non‐A, non‐B hepatitis virus with hepatitis B viral (HBV) proteins and DNA. Using molecular hybridisation under high and low stringency conditions with high specific activity 32P‐HBV DNA as a probe, serum and liver samples from patients and nonhuman primates infected with non‐A, non‐B hepatitis were examined. Our results provide no evidence of significant homology between the DNA extracted from serum and liver of patients and nonhuman primates infected with one type of non‐A, non‐B hepatitis and HBV DNA.

Original languageEnglish
Pages (from-to)205-213
Number of pages9
JournalJournal of Medical Virology
Volume12
Issue number3
DOIs
Publication statusPublished - 1983

Keywords

  • DNA molecular hybridisation
  • non‐A, non‐B hepatitis
  • nucleic acid homology

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