TY - JOUR
T1 - Fetal cystic hygromata
T2 - Insights gained from fetal blood sampling
AU - Tannirandorn, Yuen
AU - Nicolini, Umberto
AU - Nicolaidis, Peter C.
AU - Fisk, Nicholas M.
AU - Arulkumaran, Sabaratnam
AU - Rodeck, Charles H.
PY - 1990
Y1 - 1990
N2 - Twelve second‐trimester fetuses with cystic hygroma underwent fetal blood sampling for rapid karyotyping, haematologic evaluation, and blood gas analysis. An abnormal karyotype was found in seven cases: monosomy X in five, trisomy 21 in one, and trisomy 13 in the other. Eight often fetuses undergoing blood gas analysis showed hypoxaemia, five of which were growth‐retarded. Nine pregnancies were terminated. Of the remaining three, only one fetus survived the perinatal period.
AB - Twelve second‐trimester fetuses with cystic hygroma underwent fetal blood sampling for rapid karyotyping, haematologic evaluation, and blood gas analysis. An abnormal karyotype was found in seven cases: monosomy X in five, trisomy 21 in one, and trisomy 13 in the other. Eight often fetuses undergoing blood gas analysis showed hypoxaemia, five of which were growth‐retarded. Nine pregnancies were terminated. Of the remaining three, only one fetus survived the perinatal period.
KW - Cystic hygroma
KW - Fetal blood sampling
KW - Prenatal diagnosis
UR - http://www.scopus.com/inward/record.url?scp=0025360183&partnerID=8YFLogxK
U2 - 10.1002/pd.1970100309
DO - 10.1002/pd.1970100309
M3 - Article
C2 - 2343030
AN - SCOPUS:0025360183
SN - 0197-3851
VL - 10
SP - 189
EP - 193
JO - Prenatal Diagnosis
JF - Prenatal Diagnosis
IS - 3
ER -