Flipping the Target: Evaluating Natural LDHA Inhibitors for Selective LDHB Modulation

Keyphrases

• LDHA Inhibitors 100%
• Molecular Docking Analysis 50%
• Natural Product Library 50%
• In Vitro Approach 50%
• Active Binding Site 50%
• Active Sites 50%
• Uncompetitive Inhibition 50%
• Binding Mode 50%
• Uncompetitive Inhibitor 50%
• Binding Inhibition 50%
• Dimer Interface 50%
• Enzyme Kinetics Assay 50%
• Preference Feature 50%
• Substrate Preference 50%
• Comparative Docking 50%
• Reversible Interconversion 50%
• Lactate Dehydrogenase Inhibitors 50%
• Redox Cycling 50%
• Specific Behavior 50%
• Allosteric Site 50%

Biochemistry, Genetics and Molecular Biology

• LDHA 100%
• Active Site 40%
• Uncompetitive Inhibitor 20%
• Allosteric Site 20%
• Binding Site 20%
• Enzyme Kinetics 20%