TY - JOUR
T1 - Global, regional, and national burden of cancers attributable to excess body weight in 204 countries and territories, 1990 to 2019
AU - Safiri, Saeid
AU - Karamzad, Nahid
AU - Kaufman, Jay S.
AU - Nejadghaderi, Seyed Aria
AU - Bragazzi, Nicola Luigi
AU - Sullman, Mark J.M.
AU - Almasi-Hashiani, Amir
AU - Mansournia, Mohammad Ali
AU - Collins, Gary S.
AU - Kolahi, Ali Asghar
AU - Jemal, Ahmedin
N1 - Funding Information:
The Bill and Melinda Gates Foundation, which was not involved in any way in the preparation of this manuscript, funded the Global Burden of Disease study. The Shahid Beheshti University of Medical Sciences also supported the present report (grant no. 24275).
Publisher Copyright:
© 2022 The Obesity Society
PY - 2022
Y1 - 2022
N2 - Objective: The aim of this study was to report the level and trends of 13 cancers that are attributable to excess body weight (EBW) for 204 countries and territories from 1990 to 2019. Methods: The burden of cancers attributable to EBW was estimated from 1990 to 2019 based on the comparative risk assessment approach used in the Global Burden of Disease study 2019. Results: In 2019, EBW caused 11.2 million disability-adjusted life-years (DALYs), or 4.4% of all cancer-related DALYs. Between 1990 and 2019, the global EBW-attributable age-standardized cancer DALY rates (per 100,000) increased from 109.9 to 133.9, a relative increase of 21.9%. The age-standardized DALY rates (per 100,000) of cancers attributable to EBW in 2019 were highest and lowest in Mongolia (611.8) and Bangladesh (30.2), respectively. The 60- to 64-year age group had the highest number of DALYs attributable to EBW, whereas there were no large sex differences in the cancer-related burden attributable to EBW. Furthermore, the association between the age-standardized DALY rates and the sociodemographic index was generally positive. Conclusions: Overall, the EBW-attributable burden of cancers has increased in the past three decades. Public health efforts should focus on identifying appropriate preventive interventions at the population and individual levels, especially in the regions and countries with the highest burden.
AB - Objective: The aim of this study was to report the level and trends of 13 cancers that are attributable to excess body weight (EBW) for 204 countries and territories from 1990 to 2019. Methods: The burden of cancers attributable to EBW was estimated from 1990 to 2019 based on the comparative risk assessment approach used in the Global Burden of Disease study 2019. Results: In 2019, EBW caused 11.2 million disability-adjusted life-years (DALYs), or 4.4% of all cancer-related DALYs. Between 1990 and 2019, the global EBW-attributable age-standardized cancer DALY rates (per 100,000) increased from 109.9 to 133.9, a relative increase of 21.9%. The age-standardized DALY rates (per 100,000) of cancers attributable to EBW in 2019 were highest and lowest in Mongolia (611.8) and Bangladesh (30.2), respectively. The 60- to 64-year age group had the highest number of DALYs attributable to EBW, whereas there were no large sex differences in the cancer-related burden attributable to EBW. Furthermore, the association between the age-standardized DALY rates and the sociodemographic index was generally positive. Conclusions: Overall, the EBW-attributable burden of cancers has increased in the past three decades. Public health efforts should focus on identifying appropriate preventive interventions at the population and individual levels, especially in the regions and countries with the highest burden.
UR - http://www.scopus.com/inward/record.url?scp=85122883978&partnerID=8YFLogxK
U2 - 10.1002/oby.23355
DO - 10.1002/oby.23355
M3 - Article
AN - SCOPUS:85122883978
SN - 1930-7381
JO - Obesity
JF - Obesity
ER -