Global, regional and national burden of dietary iron deficiency from 1990 to 2021: a Global Burden of Disease study

  • Sooji Lee
  • , Yejun Son
  • , Jiyoung Hwang
  • , Min Seo Kim
  • , Jae Il Shin
  • , Dong Keon Yon
  • , Nicholas J. Kassebaum
  • , Semagn Mekonnen Abate
  • , Yohannes Habtegiorgis Abate
  • , Samar Abd Elhafeez
  • , Sherief Abd-Elsalam
  • , Meriem Abdoun
  • , Rizwan Suliankatchi Abdulkader
  • , Auwal Abdullahi
  • , Mesfin Abebe
  • , Armita Abedi
  • , Alemwork Abie
  • , Olumide Abiodun
  • , Richard Gyan Aboagye
  • , Hassan Abolhassani
  • Mohamed Abouzid, Lucas Guimarães Abreu, Hasan Abualruz, Hana J. Abukhadijah, Salahdein Aburuz, Ahmed Abu-Zaid, Lawan Hassan Adamu, Mesafint Molla Adane, Isaac Yeboah Addo, Oyelola A. Adegboye, Victor Adekanmbi, Charles Oluwaseun Adetunji, Temitayo Esther Adeyeoluwa, Qorinah Estiningtyas Sakilah Adnani, Leticia Akua Adzigbli, Saira Afzal, Suneth Buddhika Agampodi, Williams Agyemang-Duah, Aqeel Ahmad, Muayyad M. Ahmad, Shahzaib Ahmad, Tauseef Ahmad, Ali Ahmed, Ayman Ahmed, Haroon Ahmed, Mehrunnisha Sharif Ahmed, Syed Anees Ahmed, Marjan Ajami, Karolina Akinosoglou, Ema Akter, Salah Al Awaidy, Syed Mahfuz Al Hasan, Omar Al Omari, Muaaz M. Alajlani, Ziyad Al-Aly, Rasmieh Mustafa Al-Amer, Mohammed Albashtawy, Wafa A. Aldhaleei, Abdelazeem M. Algammal, Fadwa Naji Alhalaiqa, Abid Ali, Akhtar Ali, Liaqat Ali, Mohammed Usman Ali, Syed Shujait Ali, Waad Ali, Shohreh Alian Samakkhah, Sheikh Mohammad Alif, Sabah Al-Marwani, Hesham M. Al-Mekhlafi, Sami Almustanyir, Jaber S. Alqahtani, Rajaa M.Mohammad Al-Raddadi, Mohammed A. Alsabri, Zaid Altaany, Awais Altaf, Alaa B. Al-Tammemi, Khalid A. Altirkawi, Hany Aly, Karem H. Alzoubi, Reza Amani, Sohrab Amiri, Hubert Amu, Ganiyu Adeniyi Amusa, Robert Ancuceanu, Tudorel Andrei, Boluwatife Stephen Anuoluwa, Iyadunni Adesola Anuoluwa, Saeid Anvari, Sumadi Lukman Anwar, Anayochukwu Edward Anyasodor, Jalal Arabloo, Mosab Arafat, Aleksandr Y. Aravkin, Demelash Areda, Brhane Berhe Aregawi, Abdulfatai Aremu, Hany Ariffin, Mesay Arkew, Ketut Aryastami Ni

Research output: Contribution to journalArticlepeer-review

Abstract

Purpose Renal tumors account for approximately 7% of all childhood cancers. These include Wilms tumor (WT), clear cell sarcoma of the kidney (CCSK), malignant rhabdoid tumor of the kidney (MRTK), renal cell carcinoma (RCC), congenital mesoblastic nephroma (CMN) and other rare tumors. We investigated the epidemiology of pediatric renal tumors in Korea. Materials and Methods From January 2001 to December 2015, data of pediatric patients (0-18 years) newly-diagnosed with renal tumors at 26 hospitals were retrospectively analyzed. Results Among 439 patients (male, 240), the most common tumor was WT (n=342, 77.9%), followed by RCC (n=36, 8.2%), CCSK (n=24, 5.5%), MRTK (n=16, 3.6%), CMN (n=12, 2.7%), and others (n=9, 2.1%). Median age at diagnosis was 27.1 months (range, 0 to 225.5 months) and median follow-up duration was 88.5 months (range, 0 to 211.6 months). Overall, 32 patients died, of whom 17, 11, 1, and three died of relapse, progressive disease, second malignant neoplasm, and treatment-related mortality. Five-year overall survival and event-free survival were 97.2% and 84.8% in WT, 90.6% and 82.1% in RCC, 81.1% and 63.6% in CCSK, 60.3% and 56.2% in MRTK, and 100% and 91.7% in CMN, respectively (p < 0.001). Conclusion The pediatric renal tumor types in Korea are similar to those previously reported in other countries. WT accounted for a large proportion and survival was excellent. Non-Wilms renal tumors included a variety of tumors and showed inferior outcome, especially MRTK. Further efforts are necessary to optimize the treatment and analyze the genetic characteristics of pediatric renal tumors in Korea.
Original languageEnglish
Pages (from-to)279-290
Number of pages12
JournalCancer Research and Treatment
Volume55
Issue number1
DOIs
Publication statusPublished - 1 Jan 2023

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

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