TY - JOUR
T1 - Global, regional, and national burden of migraine in 204 countries and territories, 1990 to 2019
AU - Safiri, Saeid
AU - Pourfathi, Hojjat
AU - Eagan, Arielle
AU - Mansournia, Mohammad Ali
AU - Khodayari, Mohammad Taghi
AU - Sullman, Mark J.M.
AU - Kaufman, Jay
AU - Collins, Gary
AU - Dai, Haijiang
AU - Bragazzi, Nicola Luigi
AU - Kolahi, Ali Asghar
N1 - Funding Information:
The authors thank the Institute for Health Metrics and Evaluation staff and its collaborators who prepared these publicly available data. Also, the authors would also like to acknowledge the support of the Social Determinants of Health Research Center at the Shahid Beheshti University of Medical Sciences.
Funding Information:
The Bill and Melinda Gates Foundation, who were not involved in any way in the preparation of the present article, fund the GBD study. The Shahid Beheshti University of Medical Sciences also supported the present report (Grant No. 24493).
Funding Information:
The authors thank the Institute for Health Metrics and Evaluation staff and its collaborators who prepared these publicly available data. Also, the authors would also like to acknowledge the support of the Social Determinants of Health Research Center at the Shahid Beheshti University of Medical Sciences. Author contributions: H. Pourfathi, A.-A. Kolahi, and S. Safiri designed the study. M.A. Mansournia, M.T. Khodayari, N.L. Bragazzi, H. Dai, and S. Safiri analyzed the data and performed the statistical analyses. H. Pourfathi, A. Eagan, M.J.M. Sullman, J. Kaufman, G. Collins, and S. Safiri drafted the initial article. All authors reviewed the drafted article for critical content. All authors approved the final version of the article. The Bill and Melinda Gates Foundation, who were not involved in any way in the preparation of the present article, fund the GBD study. The Shahid Beheshti University of Medical Sciences also supported the present report (Grant No. 24493). No funding body had any role in the design, data collection, analysis, interpretation or writing of the present study nor was involved in the decision to submit for publication. This study is based on publicly available data and solely reflects the opinion of its authors and not that of the Institute for Health Metrics and Evaluation.
Publisher Copyright:
© 2021 International Association for the Study of Pain
PY - 2022/2/1
Y1 - 2022/2/1
N2 - Data from the Global Burden of Disease Study 2019 were used to report the burden of migraine in 204 countries and territories during the period 1990 to 2019, through a systematic analysis of point prevalence, annual incidence, and years lived with disability (YLD). In 2019, the global age-standardised point prevalence and annual incidence rate of migraine were 14,107.3 (95% Uncertainty Interval [UI] 12,270.3-16,239) and 1142.5 (95% UI 995.9-1289.4) per 100,000, an increase of 1.7% (95% UI 0.7%-2.8%) and 2.1% (95% UI 1.1%-2.8%) since 1990, respectively. Moreover, the global age-standardised YLD rate in 2019 was 525.5 (95% UI 78.8-1194), an increase of 1.5% (95% UI -4.4% to 3.3%) since 1990. The global point prevalence of migraine in 2019 was higher in females and increased by age up to the 40 to 44 age group, then decreased with increased age. Belgium (22,400.6 [95% UI: 19,305.2-26,215.8]), Italy (20,337.7 [95% UI: 17,724.7-23,405.8]), and Germany (19,436.4 [95% UI: 16,806.2-22,810.3]) had the 3 highest age-standardised point prevalence rates for migraine in 2019. In conclusion, there were large intercountry differences in the burden of migraine, and this burden increased significantly across the measurement period. These findings suggest that migraine care needs to be included within the health system to increase population awareness regarding the probable risk factors and treatment strategies especially among young adults and middle-aged women, as well as to increase the data on migraines.
AB - Data from the Global Burden of Disease Study 2019 were used to report the burden of migraine in 204 countries and territories during the period 1990 to 2019, through a systematic analysis of point prevalence, annual incidence, and years lived with disability (YLD). In 2019, the global age-standardised point prevalence and annual incidence rate of migraine were 14,107.3 (95% Uncertainty Interval [UI] 12,270.3-16,239) and 1142.5 (95% UI 995.9-1289.4) per 100,000, an increase of 1.7% (95% UI 0.7%-2.8%) and 2.1% (95% UI 1.1%-2.8%) since 1990, respectively. Moreover, the global age-standardised YLD rate in 2019 was 525.5 (95% UI 78.8-1194), an increase of 1.5% (95% UI -4.4% to 3.3%) since 1990. The global point prevalence of migraine in 2019 was higher in females and increased by age up to the 40 to 44 age group, then decreased with increased age. Belgium (22,400.6 [95% UI: 19,305.2-26,215.8]), Italy (20,337.7 [95% UI: 17,724.7-23,405.8]), and Germany (19,436.4 [95% UI: 16,806.2-22,810.3]) had the 3 highest age-standardised point prevalence rates for migraine in 2019. In conclusion, there were large intercountry differences in the burden of migraine, and this burden increased significantly across the measurement period. These findings suggest that migraine care needs to be included within the health system to increase population awareness regarding the probable risk factors and treatment strategies especially among young adults and middle-aged women, as well as to increase the data on migraines.
KW - Burden
KW - Epidemiology
KW - Incidence
KW - Migraine
KW - Prevalence
UR - http://www.scopus.com/inward/record.url?scp=85108986884&partnerID=8YFLogxK
U2 - 10.1097/j.pain.0000000000002275
DO - 10.1097/j.pain.0000000000002275
M3 - Article
C2 - 34001771
AN - SCOPUS:85108986884
SN - 0304-3959
VL - 163
SP - E293-E309
JO - Pain
JF - Pain
IS - 2
ER -