1. 1. Nine glycosidases in bloodstream forms of Trypanosoma brucei brucei S42 were partially characterised. 2. 2. α-Glucosidase had similar physicochemical and enzymic properties to those of α-galactosidase, β-glucosidase, N-acetyl-β-glucosaminidase and N-acetyl-β-galactosaminidase. 3. 3. α-Mannosidase was clearly distinct from the other glycosidases with respect to pH optimum, thermostability, specific activity during the course of parasitaemia, and subcellular location. 4. 4. The glycosidases studied here may play a role in the turnover of trypanosomal glycoproteins, in particular the variant-specific surface antigen.
|Number of pages||4|
|Journal||Comparative Biochemistry and Physiology -- Part B: Biochemistry and|
|Publication status||Published - 1980|