TY - JOUR
T1 - Glycosidases in bloodstream forms of Trypanosoma brucei brucei
AU - Carroll, Mark
AU - McCrorie, Peter
PY - 1980
Y1 - 1980
N2 - 1. 1. Nine glycosidases in bloodstream forms of Trypanosoma brucei brucei S42 were partially characterised. 2. 2. α-Glucosidase had similar physicochemical and enzymic properties to those of α-galactosidase, β-glucosidase, N-acetyl-β-glucosaminidase and N-acetyl-β-galactosaminidase. 3. 3. α-Mannosidase was clearly distinct from the other glycosidases with respect to pH optimum, thermostability, specific activity during the course of parasitaemia, and subcellular location. 4. 4. The glycosidases studied here may play a role in the turnover of trypanosomal glycoproteins, in particular the variant-specific surface antigen.
AB - 1. 1. Nine glycosidases in bloodstream forms of Trypanosoma brucei brucei S42 were partially characterised. 2. 2. α-Glucosidase had similar physicochemical and enzymic properties to those of α-galactosidase, β-glucosidase, N-acetyl-β-glucosaminidase and N-acetyl-β-galactosaminidase. 3. 3. α-Mannosidase was clearly distinct from the other glycosidases with respect to pH optimum, thermostability, specific activity during the course of parasitaemia, and subcellular location. 4. 4. The glycosidases studied here may play a role in the turnover of trypanosomal glycoproteins, in particular the variant-specific surface antigen.
UR - http://www.scopus.com/inward/record.url?scp=49149140312&partnerID=8YFLogxK
U2 - 10.1016/0305-0491(80)90431-9
DO - 10.1016/0305-0491(80)90431-9
M3 - Article
AN - SCOPUS:49149140312
SN - 0305-0491
VL - 67
SP - 685
EP - 688
JO - Comparative Biochemistry and Physiology -- Part B: Biochemistry and
JF - Comparative Biochemistry and Physiology -- Part B: Biochemistry and
IS - 4
ER -