Health outcome measurements in children with sleep disordered breathing

Objective: To validate the Child Health Questionnaire, measure quality of life in children with obstructive sleep apnoea and assess the impact of surgery. Methods: The primary carer of a consecutive series of 42 patients with sleep disordered breathing referred to a paediatric otolaryngology clinic completed the Child Health Questionnaire (version PF 28). Questionnaires were analysed for data quality and completeness, item/scale correlation, internal consistency and discriminant validity, interscale correlation and reliability. Following overnight pulse oximetry 37 children were diagnosed with obstructive sleep apnoea and underwent adenotonsillectomy. Results: Child Health Questionnaire Physical Functioning 28 demonstrated excellent measuring characteristics in our population. Compared with normative data, children with obstructive sleep apnoea and their carers suffer a significant quality of life deficit, involving 10 of 13 subscales of the Child Health Questionnaire. This was most prominent in parental emotional impact, general health perception and family activities. There was no correlation between the severity of obstructive sleep apnoea and quality of life indices. Following surgery, there was a significant improvement in all Child Health Questionnaire subscales, which became equivalent to healthy children. Conclusion: The Child Health Questionnaire Physical Functioning 28 is an accurate and reliable way of assessing the impact of obstructive sleep apnoea on the quality of life in children in Britain. This appears to be significant in most aspects of a child's life, but is fully reversed following surgery.