Abstract
Observational studies in humans and experimental studies in animals and isolated cells supported the widely held belief that hormone replacement therapy protects the cardiovascular system from disease. To nearly everyone's astonishment, the Women's Health Initiative Study and the Heart and Estrogen/Progestin Replacement Study overturned the conclusion that hormone replacement therapy protects the cardiovascular system and, in fact, supported the opposite view that such therapy may actually increase the risk of cardiovascular disease. This review addresses 2 questions: what went wrong and where do we go from here?
| Original language | English |
|---|---|
| Pages (from-to) | 789-795 |
| Number of pages | 7 |
| Journal | Hypertension |
| Volume | 44 |
| Issue number | 6 |
| DOIs | |
| Publication status | Published - Dec 2004 |
UN SDGs
This output contributes to the following UN Sustainable Development Goals (SDGs)
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SDG 3 Good Health and Well-being
Keywords
- Cardiovascular diseases
- Estrogen
- Hormones
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