Interactions between hepatotropic viruses in patients with haemophilia

Christine A. Lee; P. B.A. Kernoff; P. Karayiannis; Patrizia Farci; H. C. Thomas

doi:10.1016/S0168-8278(85)80775-3

Interactions between hepatotropic viruses in patients with haemophilia

Christine A. Lee, P. B.A. Kernoff, P. Karayiannis, Patrizia Farci, H. C. Thomas

Medical School

Research output: Contribution to journal › Article › peer-review

Abstract

Infections with the hepatotropic viruses non-A, non-B (NANB), hepatitis B (HBV) and delta agent (HDV) are described in two patients with haemophilia. The first patient illustrates the phenomenon of interference following a simultaneous exposure to NANB and HBV. The second patient, a carrier of hepatitis B surface antigen (HBsAg), acquired superinfection with HDV which resulted in acute hepatitis progressing to chronic hepatitis. Liver disease seen in multitransfused haemophiliacs may be significantly different to that seen in other patients. As a consequence of the infusion of blood clotting factor concentrates, these patients become the site of complex viral interactions.

Original language	English
Pages (from-to)	379-384
Number of pages	6
Journal	Journal of Hepatology
Volume	1
Issue number	4
DOIs	https://doi.org/10.1016/S0168-8278(85)80775-3
Publication status	Published - 1985

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title = "Interactions between hepatotropic viruses in patients with haemophilia",

abstract = "Infections with the hepatotropic viruses non-A, non-B (NANB), hepatitis B (HBV) and delta agent (HDV) are described in two patients with haemophilia. The first patient illustrates the phenomenon of interference following a simultaneous exposure to NANB and HBV. The second patient, a carrier of hepatitis B surface antigen (HBsAg), acquired superinfection with HDV which resulted in acute hepatitis progressing to chronic hepatitis. Liver disease seen in multitransfused haemophiliacs may be significantly different to that seen in other patients. As a consequence of the infusion of blood clotting factor concentrates, these patients become the site of complex viral interactions.",

author = "Lee, {Christine A.} and Kernoff, {P. B.A.} and P. Karayiannis and Patrizia Farci and Thomas, {H. C.}",

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AU - Lee, Christine A.

AU - Kernoff, P. B.A.

AU - Karayiannis, P.

AU - Farci, Patrizia

AU - Thomas, H. C.

PY - 1985

Y1 - 1985

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AB - Infections with the hepatotropic viruses non-A, non-B (NANB), hepatitis B (HBV) and delta agent (HDV) are described in two patients with haemophilia. The first patient illustrates the phenomenon of interference following a simultaneous exposure to NANB and HBV. The second patient, a carrier of hepatitis B surface antigen (HBsAg), acquired superinfection with HDV which resulted in acute hepatitis progressing to chronic hepatitis. Liver disease seen in multitransfused haemophiliacs may be significantly different to that seen in other patients. As a consequence of the infusion of blood clotting factor concentrates, these patients become the site of complex viral interactions.

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JO - Journal of Hepatology

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Interactions between hepatotropic viruses in patients with haemophilia

Abstract

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