Intrapartum tocolysis has no effect on fetal lactate concentration

Lennart Nordström, Selina Chua, Bengt Persson, Keiichi Naka, Sabaratnam Arulkumaran

Research output: Contribution to journalArticlepeer-review

Abstract

Objective: To assess the fetal metabolic effects of intrapartum maternal tocolysis with terbutaline in the presence of fetal heart rate abnormalities, with a special emphasis on lactate concentration, in view of its potential use as a marker of fetal condition. Design: Descriptive study. Setting: Two labour wards, National University Hospital, Singapore, and Ostersund Hospital, Sweden. Methods: Eight parturients with abnormal intrapartum fetal heart rate recordings were given bolus i.v. injection of 0.25 mg terbutaline and monitored both before and 20 minutes after treatment. Results: Maternal venous glucose increased from 5.0 (0.9) (mean (SD)) to 5.6 (1.2) mmol/l (p=0.002) and fetal scalp blood glucose rose from 4.1 (1.8) to 4.7 (1.4) mmol/l (p=0.009) 20 minutes after the injection. No significant change was found in maternal or fetal lactate concentrations. Conclusion: Terbutaline tocolysis for 'intrauterine resuscitation' does not affect fetal lactate concentration 20 minutes after treatment. Copyright (C) 2000 Elsevier Science Ireland Ltd.

Original languageEnglish
Pages (from-to)165-168
Number of pages4
JournalEuropean Journal of Obstetrics Gynecology and Reproductive Biology
Volume89
Issue number2
DOIs
Publication statusPublished - Apr 2000

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