Is chronic rhinosinusitis related to allergic rhinitis in adults and children? Applying epidemiological guidelines for causation

  • C. Georgalas
  • , I. Vlastos
  • , V. Picavet
  • , C. Van Drunen
  • , G. Garas
  • , E. Prokopakis

Research output: Contribution to journalReview articlepeer-review

Abstract

The relationship between allergic rhinitis and chronic rhinosinusitis has been assessed in a number of observational and experimental studies. In this review, we attempt their synthesis and evaluation using the modified Bradford Hill guidelines for causation. Although there is no proof of causation, especially in the pediatric literature, an evaluation of underlying allergies is recommended at least as an initial measure of symptoms relief.

Original languageEnglish
Pages (from-to)828-833
Number of pages6
JournalAllergy: European Journal of Allergy and Clinical Immunology
Volume69
Issue number7
DOIs
Publication statusPublished - Jul 2014
Externally publishedYes

Keywords

  • allergic rhinitis
  • Bradford-Hill criteria
  • causation
  • chronic rhinosinusitis

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