TY - JOUR
T1 - Lessons of the month 3
T2 - Gone but not forgotten – Osler – a reminder of the syndrome not bearing his name
AU - Mandal, Amit K.J.
AU - Mohamad, Bashir
AU - Missouris, Constantinos G.
N1 - Publisher Copyright:
© Royal College of Physicians 2019. All rights reserved.
PY - 2019
Y1 - 2019
N2 - Streptococcus pneumoniae is the most frequently implicated microbial agent in community acquired bacterial pneumonia and meningitis. It is also responsible for between 1 and 3% of cases of native valve infective endocarditis, with mortality rates up to 60%. Osler first described the association between pneumococcal pneumonia, endocarditis, and meningitis secondary to bacteria that he described as ‘micrococci’, subsequently elucidated to be S pneumoniae by Robert Austrian, and the syndrome bears his name. We report a case of fulminant pneumococcal native aortic valve endocarditis and perforation in a young male patient with chronic alcoholism and splenectomy who exhibited poor compliance to pneumococcal prophylaxis.
AB - Streptococcus pneumoniae is the most frequently implicated microbial agent in community acquired bacterial pneumonia and meningitis. It is also responsible for between 1 and 3% of cases of native valve infective endocarditis, with mortality rates up to 60%. Osler first described the association between pneumococcal pneumonia, endocarditis, and meningitis secondary to bacteria that he described as ‘micrococci’, subsequently elucidated to be S pneumoniae by Robert Austrian, and the syndrome bears his name. We report a case of fulminant pneumococcal native aortic valve endocarditis and perforation in a young male patient with chronic alcoholism and splenectomy who exhibited poor compliance to pneumococcal prophylaxis.
KW - Endocarditis
KW - Osler
KW - Splenectomy
KW - Streptococcus pneumoniae
UR - https://www.scopus.com/pages/publications/85075078919
U2 - 10.7861/clinmed.2019.0253
DO - 10.7861/clinmed.2019.0253
M3 - Article
C2 - 31732598
AN - SCOPUS:85075078919
SN - 1470-2118
VL - 19
SP - 523
EP - 525
JO - Clinical Medicine, Journal of the Royal College of Physicians of London
JF - Clinical Medicine, Journal of the Royal College of Physicians of London
IS - 6
ER -