Liposomes as bioanalytical tools

Elena A. Mourelatou, Costas Demetzos

Research output: Contribution to journalReview articlepeer-review


The interest in nanotechnology, is increasing over the past decades. Consequently an increasing number of nanotechnology's applications find practical use every day. One of them is the use of liposomes in research and analysis. Some of the advantages of liposomes as analytical and bioanalytical tools are their large internal volume, extended surface area and the ability of bilayer lipids to conjugate with a wide variety of biorecognition elements. Due to their large internal volume, liposomes have the ability to incorporate hundreds of thousands of signaling molecules, such as water soluble dyes, which leads to significant signal enhancement. This makes liposomes containing dye visually and immediately detected, even at very low concentrations, without any further processing. Liposomes have been used as biosensors in a number of studies for the detection of various microorganisms, by detecting either a specific protein or a unique mRNA sequence.

Original languageEnglish
Pages (from-to)75-81
Number of pages7
Issue number3
Publication statusPublished - 2008


Dive into the research topics of 'Liposomes as bioanalytical tools'. Together they form a unique fingerprint.

Cite this