Male hormonal contraception

C. Oxynos, F. C.W. Wu

Research output: Contribution to journalReview articlepeer-review

Abstract

Male hormonal contraceptive methods are based on the principle of pituitary gonadotrophin suppression and intratesticular testosterone depletion, leading to suppression of spermatogenesis. Following the earlier contraceptive efficacy trials using testosterone alone, synergistic combination regimes using newer androgens and other agents are now being tested. The combination of a long-acting testosterone preparation with a progestogen appears to be the most promising, and will hopefully lead to an accepted product for clinical application early in the 21st century.

Original languageEnglish
Pages (from-to)473-487
Number of pages15
JournalBest Practice and Research: Clinical Endocrinology and Metabolism
Volume14
Issue number3
DOIs
Publication statusPublished - 2000

Keywords

  • Gonadotrophin
  • Male hormonal contraception
  • Spermatogenic suppression
  • Testosterone

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