Male hormonal contraception

C. Oxynos, F. C.W. Wu

Research output: Contribution to journalReview articlepeer-review


Male hormonal contraceptive methods are based on the principle of pituitary gonadotrophin suppression and intratesticular testosterone depletion, leading to suppression of spermatogenesis. Following the earlier contraceptive efficacy trials using testosterone alone, synergistic combination regimes using newer androgens and other agents are now being tested. The combination of a long-acting testosterone preparation with a progestogen appears to be the most promising, and will hopefully lead to an accepted product for clinical application early in the 21st century.

Original languageEnglish
Pages (from-to)473-487
Number of pages15
JournalBest Practice and Research: Clinical Endocrinology and Metabolism
Issue number3
Publication statusPublished - 2000


  • Gonadotrophin
  • Male hormonal contraception
  • Spermatogenic suppression
  • Testosterone


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