Medical Treatment of Placenta Accreta with Methotrexate

S. Arulkumaran, C. S A Ng, I. Ingemarsson, S. S. Ratnam

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103 Citations (Scopus)


Placenta accreta is a rare condition and is associated with considerable maternal morbidity and mortality. Though the surgical approach of hysterectomy is a definitive therapy, there are occasions when conservation of the uterus is desired by the patient. We report a case of placenta accreta successfully treated with intravenous methotrexate. After 2 weeks of treatment no signs of placenta could be visualized on ultrasound examination of the uterus. The patient was discharged after 15 days and has since been well. Such therapy may be useful in exceptional cases in institutions with adequate facilities for careful monitoring and management of the patient. 1986 Acta Obstet Gynecol Scand

Original languageEnglish
Pages (from-to)285-286
Number of pages2
JournalActa Obstetricia et Gynecologica Scandinavica
Issue number3
Publication statusPublished - 1986


  • medical treatment
  • Placenta accreta
  • ultrasound


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