TY - JOUR
T1 - Mobile App Interventions for Parkinson’s Disease, Multiple Sclerosis and Stroke
T2 - A Systematic Literature Review
AU - Triantafyllidis, Andreas
AU - Segkouli, Sofia
AU - Zygouris, Stelios
AU - Michailidou, Christina
AU - Avgerinakis, Konstantinos
AU - Fappa, Evangelia
AU - Vassiliades, Sophia
AU - Bougea, Anastasia
AU - Papagiannakis, Nikos
AU - Katakis, Ioannis
AU - Mathioudis, Evangelos
AU - Sorici, Alexandru
AU - Bajenaru, Lidia
AU - Tageo, Valentina
AU - Camonita, Francesco
AU - Magga-Nteve, Christoniki
AU - Vrochidis, Stefanos
AU - Pedullà, Ludovico
AU - Brichetto, Giampaolo
AU - Tsakanikas, Panagiotis
AU - Votis, Konstantinos
AU - Tzovaras, Dimitrios
N1 - Funding Information:
This study has received funding from the European Union’s Horizon 2020 research and innovation program under grant agreement No 101017558 (ALAMEDA).
Publisher Copyright:
© 2023 by the authors.
PY - 2023/4
Y1 - 2023/4
N2 - Central nervous system diseases (CNSDs) lead to significant disability worldwide. Mobile app interventions have recently shown the potential to facilitate monitoring and medical management of patients with CNSDs. In this direction, the characteristics of the mobile apps used in research studies and their level of clinical effectiveness need to be explored in order to advance the multidisciplinary research required in the field of mobile app interventions for CNSDs. A systematic review of mobile app interventions for three major CNSDs, i.e., Parkinson’s disease (PD), multiple sclerosis (MS), and stroke, which impose significant burden on people and health care systems around the globe, is presented. A literature search in the bibliographic databases of PubMed and Scopus was performed. Identified studies were assessed in terms of quality, and synthesized according to target disease, mobile app characteristics, study design and outcomes. Overall, 21 studies were included in the review. A total of 3 studies targeted PD (14%), 4 studies targeted MS (19%), and 14 studies targeted stroke (67%). Most studies presented a weak-to-moderate methodological quality. Study samples were small, with 15 studies (71%) including less than 50 participants, and only 4 studies (19%) reporting a study duration of 6 months or more. The majority of the mobile apps focused on exercise and physical rehabilitation. In total, 16 studies (76%) reported positive outcomes related to physical activity and motor function, cognition, quality of life, and education, whereas 5 studies (24%) clearly reported no difference compared to usual care. Mobile app interventions are promising to improve outcomes concerning patient’s physical activity, motor ability, cognition, quality of life and education for patients with PD, MS, and Stroke. However, rigorous studies are required to demonstrate robust evidence of their clinical effectiveness.
AB - Central nervous system diseases (CNSDs) lead to significant disability worldwide. Mobile app interventions have recently shown the potential to facilitate monitoring and medical management of patients with CNSDs. In this direction, the characteristics of the mobile apps used in research studies and their level of clinical effectiveness need to be explored in order to advance the multidisciplinary research required in the field of mobile app interventions for CNSDs. A systematic review of mobile app interventions for three major CNSDs, i.e., Parkinson’s disease (PD), multiple sclerosis (MS), and stroke, which impose significant burden on people and health care systems around the globe, is presented. A literature search in the bibliographic databases of PubMed and Scopus was performed. Identified studies were assessed in terms of quality, and synthesized according to target disease, mobile app characteristics, study design and outcomes. Overall, 21 studies were included in the review. A total of 3 studies targeted PD (14%), 4 studies targeted MS (19%), and 14 studies targeted stroke (67%). Most studies presented a weak-to-moderate methodological quality. Study samples were small, with 15 studies (71%) including less than 50 participants, and only 4 studies (19%) reporting a study duration of 6 months or more. The majority of the mobile apps focused on exercise and physical rehabilitation. In total, 16 studies (76%) reported positive outcomes related to physical activity and motor function, cognition, quality of life, and education, whereas 5 studies (24%) clearly reported no difference compared to usual care. Mobile app interventions are promising to improve outcomes concerning patient’s physical activity, motor ability, cognition, quality of life and education for patients with PD, MS, and Stroke. However, rigorous studies are required to demonstrate robust evidence of their clinical effectiveness.
KW - mobile apps
KW - multiple sclerosis
KW - neurological diseases
KW - Parkinson’s disease
KW - review
KW - stroke
UR - http://www.scopus.com/inward/record.url?scp=85152321765&partnerID=8YFLogxK
U2 - 10.3390/s23073396
DO - 10.3390/s23073396
M3 - Review article
C2 - 37050456
AN - SCOPUS:85152321765
SN - 1424-8220
VL - 23
JO - Sensors
JF - Sensors
IS - 7
M1 - 3396
ER -