Nocturnal growth hormone secretion in schizophrenic patients and healthy subjects

René S. Kahn; Michael Davidson; Jack Hirschowitz; Robert G. Stern; Bonnie M. David; Steve Gabriel; Clare Moore; Kenneth L. Davis

doi:10.1016/0165-1781(92)90107-E

Nocturnal growth hormone secretion in schizophrenic patients and healthy subjects

René S. Kahn
, Michael Davidson
, Jack Hirschowitz
, Robert G. Stern
, Bonnie M. David
, Steve Gabriel
, Clare Moore
, Kenneth L. Davis

Research output: Contribution to journal › Article › peer-review

Abstract

Plasma growth hormone concentrations were measured at hourly intervals between 10 p.m. and 8 a.m. the next morning in 15 drug-free chronic schizophrenic male inpatients and 14 healthy males. Growth hormone secretion was significantly lower in the patients as compared with the controls. Growth hormone release peaked around 1 a.m. in the controls, but a growth hormone peak was absent in the patient group. Increased dopamine activity, increased serotonin activity, or both could explain the absence of a nocturnal growth hormone surge in the schizophrenic patients.

Original language	English
Pages (from-to)	155-161
Number of pages	7
Journal	Psychiatry Research
Volume	41
Issue number	2
DOIs	https://doi.org/10.1016/0165-1781(92)90107-E
Publication status	Published - Feb 1992
Externally published	Yes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

dopamine
hormones
Psychoendocrinology
serotonin

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10.1016/0165-1781(92)90107-E

Cite this

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title = "Nocturnal growth hormone secretion in schizophrenic patients and healthy subjects",

abstract = "Plasma growth hormone concentrations were measured at hourly intervals between 10 p.m. and 8 a.m. the next morning in 15 drug-free chronic schizophrenic male inpatients and 14 healthy males. Growth hormone secretion was significantly lower in the patients as compared with the controls. Growth hormone release peaked around 1 a.m. in the controls, but a growth hormone peak was absent in the patient group. Increased dopamine activity, increased serotonin activity, or both could explain the absence of a nocturnal growth hormone surge in the schizophrenic patients.",

keywords = "dopamine, hormones, Psychoendocrinology, serotonin",

author = "Kahn, \{Ren{\'e} S.\} and Michael Davidson and Jack Hirschowitz and Stern, \{Robert G.\} and David, \{Bonnie M.\} and Steve Gabriel and Clare Moore and Davis, \{Kenneth L.\}",

year = "1992",

month = feb,

doi = "10.1016/0165-1781(92)90107-E",

language = "English",

volume = "41",

pages = "155--161",

journal = "Psychiatry Research",

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TY - JOUR

T1 - Nocturnal growth hormone secretion in schizophrenic patients and healthy subjects

AU - Kahn, René S.

AU - Davidson, Michael

AU - Hirschowitz, Jack

AU - Stern, Robert G.

AU - David, Bonnie M.

AU - Gabriel, Steve

AU - Moore, Clare

AU - Davis, Kenneth L.

PY - 1992/2

Y1 - 1992/2

N2 - Plasma growth hormone concentrations were measured at hourly intervals between 10 p.m. and 8 a.m. the next morning in 15 drug-free chronic schizophrenic male inpatients and 14 healthy males. Growth hormone secretion was significantly lower in the patients as compared with the controls. Growth hormone release peaked around 1 a.m. in the controls, but a growth hormone peak was absent in the patient group. Increased dopamine activity, increased serotonin activity, or both could explain the absence of a nocturnal growth hormone surge in the schizophrenic patients.

AB - Plasma growth hormone concentrations were measured at hourly intervals between 10 p.m. and 8 a.m. the next morning in 15 drug-free chronic schizophrenic male inpatients and 14 healthy males. Growth hormone secretion was significantly lower in the patients as compared with the controls. Growth hormone release peaked around 1 a.m. in the controls, but a growth hormone peak was absent in the patient group. Increased dopamine activity, increased serotonin activity, or both could explain the absence of a nocturnal growth hormone surge in the schizophrenic patients.

KW - dopamine

KW - hormones

KW - Psychoendocrinology

KW - serotonin

UR - https://www.scopus.com/pages/publications/0026608926

U2 - 10.1016/0165-1781(92)90107-E

DO - 10.1016/0165-1781(92)90107-E

M3 - Article

C2 - 1574542

AN - SCOPUS:0026608926

SN - 0165-1781

VL - 41

SP - 155

EP - 161

JO - Psychiatry Research

JF - Psychiatry Research

IS - 2

ER -

Nocturnal growth hormone secretion in schizophrenic patients and healthy subjects

Abstract

UN SDGs

Keywords

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