TY - JOUR
T1 - Oxytocin titration to achieve preset active contraction area values does not improve the outcome of induced labour
AU - ARULKUMARAN, S.
AU - INGEMARSSON, I.
AU - RATNAM, S. S.
PY - 1987
Y1 - 1987
N2 - Summary. The value of controlling oxytocin titration in induction of labour by a preset uterine activity, assessed as active contraction area, was examined in a randomized study in 60 nulliparae and 54 multiparae. Each parity group was divided into two groups according to the cervical score (5 and >5) and within those four groups the women were randomly allocated to oxytocin titration against a preset frequency of 6–7 uterine contractions every 15 min, or to a preset uterine activity equivalent to the 75th centile for spontaneous labour. The length of labour was slightly, but not significantly, longer in the frequency group. The mode of delivery, Apgar scores at 1 and 5 min and cord artery blood pH values were similar with the two modes of oxytocin titration.The mean maximum dose rate of oxytocin infusion was not significantly different except in the nulliparous group with a poor cervical score. The given mean total dose of oxytocin was similar in the different groups when controlled for parity and cervical score. The results suggest that oxytocin titration to achieve uterine activity values equivalent to the 75th centile of those observed in spontaneous labour does not confer any advantage compared with the traditional practice of titrating the oxytocin infusion to achieve a preset frequency of uterine contractions.
AB - Summary. The value of controlling oxytocin titration in induction of labour by a preset uterine activity, assessed as active contraction area, was examined in a randomized study in 60 nulliparae and 54 multiparae. Each parity group was divided into two groups according to the cervical score (5 and >5) and within those four groups the women were randomly allocated to oxytocin titration against a preset frequency of 6–7 uterine contractions every 15 min, or to a preset uterine activity equivalent to the 75th centile for spontaneous labour. The length of labour was slightly, but not significantly, longer in the frequency group. The mode of delivery, Apgar scores at 1 and 5 min and cord artery blood pH values were similar with the two modes of oxytocin titration.The mean maximum dose rate of oxytocin infusion was not significantly different except in the nulliparous group with a poor cervical score. The given mean total dose of oxytocin was similar in the different groups when controlled for parity and cervical score. The results suggest that oxytocin titration to achieve uterine activity values equivalent to the 75th centile of those observed in spontaneous labour does not confer any advantage compared with the traditional practice of titrating the oxytocin infusion to achieve a preset frequency of uterine contractions.
UR - http://www.scopus.com/inward/record.url?scp=0023131266&partnerID=8YFLogxK
U2 - 10.1111/j.1471-0528.1987.tb02361.x
DO - 10.1111/j.1471-0528.1987.tb02361.x
M3 - Article
C2 - 3567121
AN - SCOPUS:0023131266
SN - 1470-0328
VL - 94
SP - 242
EP - 248
JO - BJOG: An International Journal of Obstetrics & Gynaecology
JF - BJOG: An International Journal of Obstetrics & Gynaecology
IS - 3
ER -