Persistence of chlamydial infection after treatment for neonatal conjunctivitis

E. Rees, I. A. Tait, D. Hobson, P. Karayiannis, N. Lee

Research output: Contribution to journalArticle

34 Citations (Scopus)

Abstract

A high incidence of pharyngeal infection was found in babies with isolation-positive chlamydial conjunctivitis. Chlamydia trachomatis was isolated from the pharynx of 12 (52%) of 23 babies before treatment, and was reisolated from the eyes of 4 (12%) of 34 and from the pharynx of 14 (41%) of 34 after treatment. C trachomatis was reisolated significantly more often from babies treated only with topical tetracycline for 4 weeks (75%) than from those treated with both topical tetracycline and oral erythromycin for 2 weeks (32%). Reisolation from the eyes was associated with only minor clinical signs. Radiological signs of an inflammatory lesion in the chest were found in 2 of 8 babies examined because of persistent cough. These signs were not associated with high or rising titres of serum chlamydial antibody.

Original languageEnglish
Pages (from-to)193-198
Number of pages6
JournalArchives of Disease in Childhood
Volume56
Issue number3
Publication statusPublished - 1981

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Conjunctivitis
Pharynx
Tetracycline
Chlamydia trachomatis
Erythromycin
Infection
Cough
Thorax
Antibodies
Incidence
Serum

Cite this

Rees, E. ; Tait, I. A. ; Hobson, D. ; Karayiannis, P. ; Lee, N. / Persistence of chlamydial infection after treatment for neonatal conjunctivitis. In: Archives of Disease in Childhood. 1981 ; Vol. 56, No. 3. pp. 193-198.
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Persistence of chlamydial infection after treatment for neonatal conjunctivitis. / Rees, E.; Tait, I. A.; Hobson, D.; Karayiannis, P.; Lee, N.

In: Archives of Disease in Childhood, Vol. 56, No. 3, 1981, p. 193-198.

Research output: Contribution to journalArticle

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