Platelet 3H-imipramine binding in pregnancy and the puerperium

  • Cornelius L.E. Katona
  • , Andreas E. Theodorou
  • , Constantinos G. Missouris
  • , Michael P. Bourke
  • , Roger W. Horton
  • , Deborah Moncrieff
  • , Eugene S. Paykel
  • , John S. Kelly

Research output: Contribution to journalArticlepeer-review

Abstract

Platelet 3H-imipramine binding was examined in a cross-sectional study of 70 Caucasian women in pregnancy and the early post-partum period, and in 23 nonpregnant women of childbearing age. Mood was also assessed in the pregnancy and post-partum sample. No significant differences in number of binding sites (Bmax) were found, but an increase in the equilibrium dissociation constant (Kd) was demonstrated at 5-7 days post-partum.

Original languageEnglish
Pages (from-to)33-37
Number of pages5
JournalPsychiatry Research
Volume14
Issue number1
DOIs
Publication statusPublished - Jan 1985
Externally publishedYes

Keywords

  • Platelet imipramine binding
  • post-partum
  • pregnancy

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