An antigen/antibody system associated with one form of parenterally transmitted non‐A, non‐B (NANB) hepatitis has been identified by solid‐phase radioimmunoassay (RIA). The antigen is found in 3% of normal subjects and in increased frequency in patients with haemophilia, renal homograft recipients, homosexual men, prostitutes, drug addicts, and patients with chronic hepatitis B virus (HBV) infection. The antigen was found in normal frequency in patients with acute hepatitis A and B, sporadic NANB hepatitis (nondrug addicts), autoimmune and alcohol‐induced chronic liver disease, and primary biliary chirrhosis.
- antigen/antibody system
- non‐B hepatitis