Prevalence of a non‐A, non‐B‐associated antigen/antibody system detected by radioimmunoassay in acute and chronic liver disease

Kang‐Xian ‐X Luo, Peter Karayiannis, David Macdonald Burns, May Bamber, Peter Kernoff, Howard Thomas

Research output: Contribution to journalArticlepeer-review

6 Citations (Scopus)

Abstract

An antigen/antibody system associated with one form of parenterally transmitted non‐A, non‐B (NANB) hepatitis has been identified by solid‐phase radioimmunoassay (RIA). The antigen is found in 3% of normal subjects and in increased frequency in patients with haemophilia, renal homograft recipients, homosexual men, prostitutes, drug addicts, and patients with chronic hepatitis B virus (HBV) infection. The antigen was found in normal frequency in patients with acute hepatitis A and B, sporadic NANB hepatitis (nondrug addicts), autoimmune and alcohol‐induced chronic liver disease, and primary biliary chirrhosis.

Original languageEnglish
Pages (from-to)253-265
Number of pages13
JournalJournal of Medical Virology
Volume12
Issue number4
DOIs
Publication statusPublished - 1983

Keywords

  • antigen/antibody system
  • non‐A
  • non‐B hepatitis
  • radioimmunoassay

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