Respiration effect on peripheral microcirculation dynamics

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

Monitoring peripheral microcirculation (PM) through changes in peripheral blood flow and oxygenation may both alert an early onset of disease and provide information about effectiveness of treatment. We investigated the correlation between changes in PM and breathing using a commercial device that guides its user from normal- to slow breathing. Capillary blood flow and transcutaneous oxygen tension (tcPO2) signals were measured before, during and after the breathing guiding. We investigated the interaction between respiration and the PM-related measures at different respiration rates. We found that 1) Respiration entrained dynamically the capillary flow at respiration rate of 6-8 breaths/min but not at other rates, and 2) As respiration became slow tcPO2 increased if it initial level was high and decreased if initially low. These results enhance our insight regarding the manner, in which skin blood flow is controlled by respiration at an individual subject and therefore may have important clinical potential regarding the PM functionality under various physiological and clinical conditions.

Original languageEnglish
Title of host publication6th European Conference of the International Federation for Medical and Biological Engineering - MBEC 2014
EditorsIgor Lackovic, Darko Vasic
PublisherSpringer Verlag
Pages460-463
Number of pages4
ISBN (Electronic)9783319111278
DOIs
Publication statusPublished - 2015
Externally publishedYes
Event6th European Conference of the International Federation for Medical and Biological Engineering, MBEC 2014 - Dubrovnik, Croatia
Duration: 7 Sept 201411 Sept 2014

Publication series

NameIFMBE Proceedings
Volume45
ISSN (Print)1680-0737

Other

Other6th European Conference of the International Federation for Medical and Biological Engineering, MBEC 2014
Country/TerritoryCroatia
CityDubrovnik
Period7/09/1411/09/14

Keywords

  • Blood flow
  • Device-guided breathing
  • Peripheral microcirculation
  • Transcutaneous oxygen tension

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