Response to Combination Cholinergic/Noradrenergic Treatments in a Patient With Alzheimer's Disease

Paul S. Aisen; Linda M. Bierer; Michael Davidson; Theresa M. Ryan; Ranti Kaminsky; Kenneth L. Davis

doi:10.1097/00019442-199300130-00009

Response to Combination Cholinergic/Noradrenergic Treatments in a Patient With Alzheimer's Disease

Paul S. Aisen
, Linda M. Bierer
, Michael Davidson
, Theresa M. Ryan
, Ranti Kaminsky
, Kenneth L. Davis

Research output: Contribution to journal › Article › peer-review

Abstract

A patient with probable Alzheimer's disease participated in four studies involving cholinergic and combination cholinergic/noradrenergic treatment regimens. This patient demonstrated clinically significant improvement only with the combination of physostigmine and clonidine. The implications of these findings are discussed with regard to strategies for neurotransmitter augmentation therapy for Alzheimer's disease.

Original language	English
Pages (from-to)	244-248
Number of pages	5
Journal	American Journal of Geriatric Psychiatry
Volume	1
Issue number	3
DOIs	https://doi.org/10.1097/00019442-199300130-00009
Publication status	Published - 1993
Externally published	Yes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

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10.1097/00019442-199300130-00009

Cite this

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title = "Response to Combination Cholinergic/Noradrenergic Treatments in a Patient With Alzheimer's Disease",

abstract = "A patient with probable Alzheimer's disease participated in four studies involving cholinergic and combination cholinergic/noradrenergic treatment regimens. This patient demonstrated clinically significant improvement only with the combination of physostigmine and clonidine. The implications of these findings are discussed with regard to strategies for neurotransmitter augmentation therapy for Alzheimer's disease.",

author = "Aisen, \{Paul S.\} and Bierer, \{Linda M.\} and Michael Davidson and Ryan, \{Theresa M.\} and Ranti Kaminsky and Davis, \{Kenneth L.\}",

year = "1993",

doi = "10.1097/00019442-199300130-00009",

language = "English",

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AU - Aisen, Paul S.

AU - Bierer, Linda M.

AU - Davidson, Michael

AU - Ryan, Theresa M.

AU - Kaminsky, Ranti

AU - Davis, Kenneth L.

PY - 1993

Y1 - 1993

N2 - A patient with probable Alzheimer's disease participated in four studies involving cholinergic and combination cholinergic/noradrenergic treatment regimens. This patient demonstrated clinically significant improvement only with the combination of physostigmine and clonidine. The implications of these findings are discussed with regard to strategies for neurotransmitter augmentation therapy for Alzheimer's disease.

AB - A patient with probable Alzheimer's disease participated in four studies involving cholinergic and combination cholinergic/noradrenergic treatment regimens. This patient demonstrated clinically significant improvement only with the combination of physostigmine and clonidine. The implications of these findings are discussed with regard to strategies for neurotransmitter augmentation therapy for Alzheimer's disease.

UR - https://www.scopus.com/pages/publications/85025404644

U2 - 10.1097/00019442-199300130-00009

DO - 10.1097/00019442-199300130-00009

M3 - Article

AN - SCOPUS:85025404644

SN - 1064-7481

VL - 1

SP - 244

EP - 248

JO - American Journal of Geriatric Psychiatry

JF - American Journal of Geriatric Psychiatry

IS - 3

ER -

Response to Combination Cholinergic/Noradrenergic Treatments in a Patient With Alzheimer's Disease

Abstract

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